Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 3/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6692232 | 0.87 | KMT2A (0.49) | HTR4ACHEHTTGAASLC29A1 | |
| SCHEMBL6692578 | 0.84 | LMNA (0.47) | HTR4ACHEGAAKMT2AALDH1A1 | |
| SCHEMBL6692407 | 0.83 | KMT2A (0.54) | HTTGAASLC29A1POLBKMT2A | |
| SCHEMBL6692413 | 0.83 | KMT2A (0.53) | HTR4HTTGAASLC29A1POLB | |
| SCHEMBL6692012 | 0.81 | CA2 (0.42) | HTR4ACHE | |
| SCHEMBL6930889 | 0.77 | CA12 (0.50) | SLC29A1POLBKMT2AMEN1ALDH1A1 | |
| SCHEMBL6697103 | 0.77 | PARP1 (0.43) | HTTGAAPOLBKMT2AMEN1 | |
| SCHEMBL5573082 | 0.75 | LMNA (0.47) | GAASLC29A1POLBKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL5570671 | 0.74 | LMNA (0.46) | GAASLC29A1POLBKMT2AMEN1 | |
| SCHEMBL22172135 | 0.74 | ALDH1A1 (0.52) | HTR4ACHEHTTGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004074438-A2 | CCR8 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-09-02 | — | — | WO | claimed |