Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 6/20 | 0.59 |
| ▸ | HTR6 | P50406 | 5/20 | 0.48 |
| ▸ | HTR1A | P08908 | 3/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR5A | P47898 | 1/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | STAT6 | P42226 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6694787 | 0.88 | HTR7 (0.48) | HTR7HTR6HTR1AHTR2AHTR5A | |
| SCHEMBL6694173 | 0.80 | IDO1 (0.42) | HTR7HTR6HTR1APTGDR2 | |
| SCHEMBL941809 | 0.76 | HTR7 (1.00) | HTR7HTR6HTR1AHTR2AHTR5A | |
| SCHEMBL6700145 | 0.76 | HTR1A (0.40) | HTR7HTR6HTR1AHTR2AHTR3A | |
| SCHEMBL6693288 | 0.75 | HTR7 (0.48) | HTR7HTR6HTR1AHTR2A | |
| SCHEMBL9584191 | 0.74 | APP (0.53) | HTR6HTR2APTGDR2 | |
| SCHEMBL6696172 | 0.73 | HTR6 (0.49) | HTR7HTR6HTR1A | |
| SCHEMBL7844529 | 0.73 | SIGMAR1 (0.52) | HTR7HTR6HTR1AHTR5AHTR3A | |
| SCHEMBL6700742 | 0.72 | PTGDR2 (0.43) | HTR7HTR6HTR1APTGDR2HTR3A | |
| SCHEMBL4943532 | 0.71 | HTR6 (0.52) | HTR6PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040229874-A1 | 5HT7 Antagonists and inverse agonists | PFIZER INC. | 2004-11-18 | — | — | US | claimed |
| US-20040229874-A1 | 5HT7 Antagonists and inverse agonists | PFIZER INC. | 2004-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040229874-A1 | 5HT7 Antagonists and inverse agonists | HTR7, HTR1A, HTR1B | HTR7 1/4885HTR6 13/4885HTR1A 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.