Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 8/20 | 0.48 |
| ▸ | HTR6 | P50406 | 4/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | HTR5A | P47898 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6693288 | 0.88 | HTR7 (0.48) | HTR7HTR6HTR1AHTR2APPARG | |
| SCHEMBL6692591 | 0.88 | HTR7 (0.59) | HTR7HTR6HTR1AHTR2AHTR5A | |
| SCHEMBL6700145 | 0.76 | HTR1A (0.40) | HTR7HTR6HTR1AHTR2APPARG | |
| SCHEMBL3861264 | 0.74 | APP (0.53) | HTR7HTR6HTR2AHDAC3HDAC4 | |
| SCHEMBL27976945 | 0.74 | HTR2A (0.55) | HTR7HTR6HTR2AHDAC3HDAC4 | |
| SCHEMBL6696172 | 0.73 | HTR6 (0.49) | HTR7HTR6HTR1AHDAC1HDAC2 | |
| SCHEMBL7844529 | 0.73 | SIGMAR1 (0.52) | HTR7HTR6HTR1AHTR5AADRB1 | |
| SCHEMBL6695065 | 0.72 | HTR7 (0.45) | HTR7HTR1APPARGHRH4HTR2C | |
| SCHEMBL27976943 | 0.71 | HTR6 (0.52) | HTR6PPARGHDAC3HDAC4HDAC1 | |
| SCHEMBL6086626 | 0.70 | HDAC8 (0.55) | HTR7HTR6HTR2AHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040229874-A1 | 5HT7 Antagonists and inverse agonists | PFIZER INC. | 2004-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040229874-A1 | 5HT7 Antagonists and inverse agonists | HTR7, HTR1A, HTR1B | HTR7 1/4885HTR6 13/4885HTR1A 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.