Phosphine

Phosphine

SCHEMBL6693796

CCCCC(Cl)(CCCC)CCCC.P

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FDPS P14324 3/20 0.39
TSHR P16473 4/20 0.38
LMNA P02545 1/20 0.38
TDP1 Q9NUW8 1/20 0.37
THRB P10828 1/20 0.35
ALDH1A1 P00352 2/20 0.33
SMPD1 P17405 2/20 0.31
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5528900 0.97 TSHR (0.40) FDPSTSHRLMNATDP1THRB
Phosphine SCHEMBL4651873 0.94 FDPS (0.39) FDPSTSHRTHRBALDH1A1SMPD1
Ammonia Solution, Strong SCHEMBL524093 0.93 FDPS (0.39) FDPSTSHRLMNATDP1THRB
SCHEMBL27696187 0.93 FDPS (0.39) FDPSTSHRLMNATDP1THRB
SCHEMBL27810873 0.90 FDPS (0.37) FDPSTSHRLMNATDP1THRB
Phosphine SCHEMBL6050501 0.88 TSHR (0.47) FDPSTSHRTHRBALDH1A1SMPD1
Ammonia Solution, Strong SCHEMBL11836898 0.88 FDPS (0.39) FDPSTSHRTHRBALDH1A1SMPD1
Phosphine SCHEMBL6694555 0.88 TSHR (0.47) FDPSTSHRTHRBALDH1A1SMPD1
Ammonia Solution, Strong SCHEMBL11827544 0.88 FDPS (0.39) FDPSTSHRTHRBALDH1A1SMPD1
SCHEMBL27965072 0.88 TSHR (0.47) FDPSTSHRTHRBALDH1A1SMPD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9000214-B2 Process for purifying terephthalic acid using ionic liquids UOP LLC (US) 2015-04-07 US disclosed
US-20130331603-A1 Process for Purifying Terephthalic Acid Using Ionic Liquids UOP LLC 2013-12-12 US disclosed
US-20040181099-A1 Aromatic ethers and process for producing aromatic ethers NIPPON SHOKUBAI CO., LTD. (JP) 2004-09-16 US disclosed
EP-0139404-B1 BIOCIDAL WATER TREATMENT Albright & Wilson Limited (GB) 1988-02-03 EP disclosed
US-4673509-A ADDING PHOSPHONIUM COMPOUND ALBRIGHT & WILSON LIMITED (GB) 1987-06-16 US disclosed
EP-0139404-A1 Biocidal water treatment Albright & Wilson Limited (GB) 1985-05-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040181099-A1 Aromatic ethers and process for producing aromatic ethers XDH, FTO, CYP4F8 FDPS 422/4885TSHR 1258/4885LMNA 4621/4885
US-20130331603-A1 Process for Purifying Terephthalic Acid Using Ionic Liquids TST, PAH, OGDH FDPS 3574/4885TSHR 1365/4885LMNA 3487/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.