Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11795754 | 0.91 | MAOA (0.47) | MAOAMAOBCYP2C9ACSL1MAPKAPK2 | |
| SCHEMBL83906 | 0.90 | MAOA (0.48) | MAOAMAOBCYP2C9ACSL1MAPKAPK2 | |
| SCHEMBL9151406 | 0.82 | MAOA (0.41) | MAOAMAOBCYP2C9ACSL1MAPKAPK2 | |
| SCHEMBL8198726 | 0.80 | MAOA (0.52) | MAOAMAOBCYP2C9ACSL1MAPKAPK2 | |
| SCHEMBL5692 | 0.80 | MAOA (0.52) | MAOAMAOBCYP2C9ACSL1MAPKAPK2 | |
| SCHEMBL7554503 | 0.79 | TRPA1 (0.50) | MAOAMAOBCYP2C9MAPKAPK2TRPA1 | |
| Hydrochloric Acid SCHEMBL6864147 | 0.79 | MAOA (0.50) | MAOAMAOBCYP2C9ACSL1MAPKAPK2 | |
| Ammonia Solution, Strong SCHEMBL7709867 | 0.79 | MAOA (0.50) | MAOAMAOBCYP2C9ACSL1MAPKAPK2 | |
| Water SCHEMBL8596209 | 0.78 | MAOA (0.48) | MAOAMAOBCYP2C9ACSL1MAPKAPK2 | |
| Carbonotrithioic Acid SCHEMBL18320929 | 0.77 | CYP2C9 (0.41) | MAOAMAOBCYP2C9ACSL1MAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040054195-A1 | Fluorescent dyes; photostability; labels, staining; analysis | NORTHEASTERN UNIVERSITY | 2004-03-18 | — | — | US | disclosed |
| WO-2002055512-A1 | XANTHENE DERIVATIVES | NORTHEASTERN UNIVERSITY (US) | 2002-07-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040054195-A1 | Fluorescent dyes; photostability; labels, staining; analysis | ANXA5, XDH, TFEB | MAOA 86/4885MAOB 99/4885CYP2C9 857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.