Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6225743 | 0.79 | CA12 (0.56) | MAPK1ALDH1A1HDAC6HDAC1CXCR2 | |
| SCHEMBL1249731 | 0.77 | MAPK1 (0.58) | MAPK1ALDH1A1CXCR2MAOBHPGD | |
| SCHEMBL9765618 | 0.77 | CYP11B1 (0.61) | HDAC6HDAC1CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL12489603 | 0.76 | ALDH1A1 (0.83) | MAPK1ALDH1A1MAOBHPGDTSHR | |
| SCHEMBL6251334 | 0.75 | ALDH1A1 (0.60) | MAPK1ALDH1A1MAOBHPGDTSHR | |
| SCHEMBL1247379 | 0.75 | MAPK1 (0.60) | MAPK1ALDH1A1MAOBHPGDTSHR | |
| SCHEMBL6691960 | 0.74 | HTR6 (0.59) | MAPK1ALDH1A1HDAC6HDAC1MGLL | |
| SCHEMBL1241108 | 0.74 | CYP11B1 (0.57) | ALDH1A1HDAC6HDAC1CYP11B1CYP11B2 | |
| SCHEMBL6696152 | 0.73 | HDAC8 (0.44) | MAPK1ALDH1A1HDAC6HDAC1CYP11B1 | |
| SCHEMBL12514860 | 0.73 | ALDH1A1 (0.58) | MAPK1ALDH1A1HPGDTSHRCXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040229874-A1 | 5HT7 Antagonists and inverse agonists | PFIZER INC. | 2004-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040229874-A1 | 5HT7 Antagonists and inverse agonists | HTR7, HTR1A, HTR1B | MAPK1 1987/4885ALDH1A1 1099/4885HDAC6 1841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.