Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INSR | P06213 | 1/20 | 0.56 |
| ▸ | IGF1R | P08069 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALPG | P10696 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 2/20 | 0.43 |
| ▸ | MC5R | P33032 | 2/20 | 0.43 |
| ▸ | MC3R | P41968 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6692765 | 0.92 | INSR (0.49) | INSRIGF1RFFAR1MRGPRX4MAPT | |
| SCHEMBL6154500 | 0.88 | INSR (0.59) | INSRIGF1RFFAR1MRGPRX4MAPT | |
| SCHEMBL6694209 | 0.87 | MAPT (0.63) | INSRIGF1RMAPTMEN1KMT2A | |
| SCHEMBL20036943 | 0.84 | INSR (0.75) | INSRIGF1RFFAR1MRGPRX4CYP1A2 | |
| SCHEMBL6696002 | 0.82 | MAPT (0.64) | INSRIGF1RFFAR1MRGPRX4MAPT | |
| SCHEMBL27527525 | 0.81 | FFAR1 (0.60) | INSRIGF1RFFAR1MRGPRX4MEN1 | |
| Hydrochloric Acid SCHEMBL6419281 | 0.80 | FFAR1 (0.58) | INSRIGF1RFFAR1MRGPRX4MEN1 | |
| SCHEMBL6694203 | 0.78 | MRGPRX4 (0.56) | IGF1RMRGPRX4MAPTMEN1KMT2A | |
| SCHEMBL6693884 | 0.78 | AGER (0.51) | MRGPRX4MAPTMEN1KMT2AHDAC8 | |
| SCHEMBL9702743 | 0.78 | INSR (0.67) | INSRIGF1RFFAR1MRGPRX4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040009973-A1 | Phenylenediamine derivatives N-substituted with benzyl- or heteroarylmethyl- groups | 4SC AG (DE) | 2004-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040009973-A1 | Phenylenediamine derivatives N-substituted with benzyl- or heteroarylmethyl- groups | PAH, PNMT, OPRM1 | INSR 898/4885IGF1R 2296/4885FFAR1 1914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.