SCHEMBL6696764

SCHEMBL6696764

CC(O[SiH3])c1ccccc1C(C)C(C)N

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
NFKB1 P19838 1/20 0.34
PNMT P11086 1/20 0.34
LMNA P02545 2/20 0.33
ALDH1A1 P00352 2/20 0.33
GLA P06280 1/20 0.33
ADRA2A P08913 1/20 0.32
ADRA2C P18825 1/20 0.32
HIF1A Q16665 1/20 0.32
KDM4E B2RXH2 1/20 0.32
GABRA1 P14867 1/20 0.30
GABRB2 P47870 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL705405 0.79 GABRA1 (0.44) CYP1A2CYP3A4LMNAADRA2AADRA2C
SCHEMBL10631769 0.77 TSHR (0.37) ALDH1A1KDM4E
SCHEMBL704522 0.72 ESR1 (0.52) CYP2D6CYP3A4LMNAALDH1A1ADRA2A
SCHEMBL713134 0.72 ALDH1A1 (0.39) CYP3A4ALDH1A1GABRA1GABRB2
SCHEMBL28724146 0.72 TSHR (0.39) GABRA1GABRB2
SCHEMBL28724160 0.72 TSHR (0.53) ALDH1A1KDM4EGABRA1GABRB2
SCHEMBL6699017 0.72 SLC6A2 (0.42) ADRA2A
SCHEMBL2679560 0.70 CYP3A4 (0.41) CYP2D6CYP1A2CYP3A4NFKB1PNMT
SCHEMBL3481876 0.69 TSHR (0.37) ADRA2AADRA2C
SCHEMBL24920007 0.68 IDO1 (0.41) CYP2D6CYP1A2CYP3A4NFKB1PNMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040197484-A1 Coating liquid for forming insulating film and method for producing insulating film SUMITOMO CHEMICAL COMPANY, LIMITED 2004-10-07 US disclosed