SCHEMBL6699017

SCHEMBL6699017

CC(N)Cc1ccccc1C(C)O[SiH3]

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 3/20 0.42
TAAR1 Q96RJ0 2/20 0.42
SLC6A4 P31645 2/20 0.42
SLC6A3 Q01959 2/20 0.42
MAOA P21397 1/20 0.42
SIGMAR1 Q99720 1/20 0.42
CYP2A6 P11509 1/20 0.42
ADORA2A P29274 1/20 0.42
ADORA1 P30542 1/20 0.42
KMT2A Q03164 2/20 0.41
HTR2A P28223 3/20 0.40
ADRB1 P08588 1/20 0.40
HTR1A P08908 1/20 0.40
ADRA2A P08913 1/20 0.40
HTR1D P28221 1/20 0.40
HTR1B P28222 1/20 0.40
HTR2C P28335 1/20 0.40
HTR1E P28566 1/20 0.40
HTR7 P34969 1/20 0.40
HTR2B P41595 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL705287 0.79 MAPT (0.39) SLC6A2SLC6A4SLC6A3ADRA2A
SCHEMBL15820759 0.79 SLC6A2 (0.50) SLC6A2TAAR1SLC6A4SLC6A3MAOA
SCHEMBL4318969 0.76 KMT2A (0.45) SLC6A2TAAR1SLC6A4SLC6A3MAOA
SCHEMBL708783 0.76 ADRA2A (0.51) HTR1AADRA2A
SCHEMBL9716522 0.76 ADRA2A (0.36) TAAR1MAOAHTR2AADRA2A
SCHEMBL2857779 0.76 SLC6A2 (0.61) SLC6A2TAAR1SLC6A4SLC6A3MAOA
SCHEMBL28002408 0.76 SLC6A2 (0.47) SLC6A2TAAR1SLC6A4SLC6A3MAOA
SCHEMBL16541142 0.74 ADRA2C (0.53) SLC6A2SLC6A4KMT2AADRB1HTR1A
SCHEMBL706042 0.74 ADRA2A (0.43) ADRA2A
SCHEMBL10631769 0.73 TSHR (0.37) SLC6A2TAAR1SLC6A4SLC6A3MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040197484-A1 Coating liquid for forming insulating film and method for producing insulating film SUMITOMO CHEMICAL COMPANY, LIMITED 2004-10-07 US disclosed