Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100B | P04271 | 1/20 | 0.47 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.35 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LGMN | Q99538 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6708640 | 0.87 | S100B (0.49) | S100BGAARAD52CRHR1IGLV6-57 | |
| SCHEMBL6696875 | 0.82 | ALDH1A1 (0.40) | AAK1GAARAD52MAPTLMNA | |
| SCHEMBL10798964 | 0.76 | S100B (0.62) | S100BGAARAD52CRHR1IGLV6-57 | |
| Hydrochloric Acid SCHEMBL8385619 | 0.74 | S100B (0.61) | S100BGAARAD52IGLV6-57MAPT | |
| SCHEMBL8983637 | 0.74 | S100B (0.61) | S100BGAARAD52CRHR1IGLV6-57 | |
| SCHEMBL11629765 | 0.74 | GAA (0.42) | GAAMAPTLMNAMEN1PKM | |
| SCHEMBL7031493 | 0.73 | SMN1; SMN2 (0.34) | MAPTHTTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL7032819 | 0.73 | S100B (0.59) | S100BGAARAD52CRHR1IGLV6-57 | |
| SCHEMBL793451 | 0.73 | S100B (0.59) | S100BGAARAD52CRHR1IGLV6-57 | |
| SCHEMBL11114625 | 0.73 | S100B (0.59) | S100BGAARAD52CRHR1IGLV6-57 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0506549-B1 | Dyeing composition for keratinous fibers containing oxidation dye precursors and hydroxybenzofurans as couplers and dyeing process making use of such a composition | OREAL (FR) | 1995-10-18 | — | — | EP | claimed |
| EP-0446132-B1 | Keratinous fibres dyeing process with 6 or 7-monohydroxyindols at acidic pH and compositions | OREAL (FR) | 1994-09-14 | — | — | EP | claimed |
| US-5203875-A | Hair dyes also using ortho- and para-phenylenediamines or aminophenols; colorfastness; washfastness; perspiration resistance | L'OREAL (FR) | 1993-04-20 | — | — | US | claimed |
| US-20040158941-A1 | Hair colouring and conditioning compositions | THE PROCTER & GAMBLE COMPANY (US) | 2004-08-19 | — | — | US | disclosed |
| US-20040158938-A1 | Method for colouring hair | THE PROCTER & GAMBLE COMPANY | 2004-08-19 | — | — | US | disclosed |
| US-20030113286-A1 | Hair colouring and conditioning compositions | THE PROCTER & GAMBLE COMPANY (US) | 2003-06-19 | — | — | US | disclosed |
| US-20030110579-A1 | Method for colouring hair | THE PROCTER & GAMBLE COMPANY (US) | 2003-06-19 | — | — | US | disclosed |
| US-5207798-A | Hair dyes | L'OREAL (FR) | 1993-05-04 | — | — | US | disclosed |
| US-5203875-A | Hair dyes also using ortho- and para-phenylenediamines or aminophenols; colorfastness; washfastness; perspiration resistance | L'OREAL (FR) | 1993-04-20 | — | — | US | disclosed |
| US-4566875-A | HAIR DYES | L'OREAL (FR) | 1986-01-28 | — | — | US | disclosed |
| US-4289495-A | HAIR DYES, STORAGE STABILITY | L'OREAL (FR) | 1981-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030110579-A1 | Method for colouring hair | COX5B, SHH, DNMT3A | S100B 93/4885AAK1 4313/4885GAA 4055/4885 |
| US-20040158941-A1 | Hair colouring and conditioning compositions | FNIP1, CUTA, SHH | S100B 237/4885AAK1 3970/4885GAA 4604/4885 |
| US-20040158938-A1 | Method for colouring hair | COX5B, SHH, DNMT3A | S100B 93/4885AAK1 4313/4885GAA 4055/4885 |
| US-20030113286-A1 | Hair colouring and conditioning compositions | FNIP1, CUTA, SHH | S100B 237/4885AAK1 3970/4885GAA 4604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.