SCHEMBL6696875

SCHEMBL6696875

CCN(c1ccc(N)cc1)C(C)N1CCOCC1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.40
▸ MAPK1 P28482 3/20 0.40
▸ GFER P55789 2/20 0.40
▸ TSHR P16473 2/20 0.40
▸ CYP3A4 P08684 2/20 0.40
▸ TDP1 Q9NUW8 2/20 0.40
▸ PSMD14 O00487 1/20 0.40
▸ RECQL P46063 1/20 0.40
▸ L3MBTL1 Q9Y468 1/20 0.40
▸ PIK3R1 P27986 1/20 0.36
▸ PIK3CA P42336 1/20 0.36
▸ MTOR P42345 1/20 0.36
▸ NR1H2 P55055 1/20 0.36
▸ NR1H3 Q13133 1/20 0.36
▸ MAPT P10636 5/20 0.36
▸ SMN1; SMN2 Q16637 4/20 0.36
▸ GAA P10253 3/20 0.36
▸ NPC1 O15118 2/20 0.36
▸ RAB9A P51151 2/20 0.36
▸ KDM4E B2RXH2 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6705808 0.85 ALDH1A1 (0.42) ALDH1A1MAPK1GFERTSHRCYP3A4
SCHEMBL6696798 0.82 S100B (0.47) ALDH1A1NR1H2NR1H3MAPTSMN1; SMN2
SCHEMBL11629765 0.82 GAA (0.42) ALDH1A1MAPK1TSHRTDP1L3MBTL1
SCHEMBL7031493 0.73 SMN1; SMN2 (0.34) ALDH1A1MAPK1TSHRMAPTSMN1; SMN2
SCHEMBL1143293 0.71 ALDH1A1 (0.56) ALDH1A1MAPK1GFERTSHRCYP3A4
Hydrochloric Acid SCHEMBL1143292 0.70 ALDH1A1 (0.54) ALDH1A1MAPK1GFERTSHRCYP3A4
SCHEMBL263756 0.69 LTA4H (0.49) ALDH1A1TSHRCYP3A4PIK3R1PIK3CA
SCHEMBL526297 0.69 TDP1 (0.52) ALDH1A1MAPK1GFERTSHRCYP3A4
SCHEMBL9856682 0.69 TDP1 (0.52) ALDH1A1MAPK1GFERTSHRCYP3A4
SCHEMBL6708640 0.68 S100B (0.49) ALDH1A1GFERTSHRCYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0506549-B1 Dyeing composition for keratinous fibers containing oxidation dye precursors and hydroxybenzofurans as couplers and dyeing process making use of such a composition OREAL (FR) 1995-10-18 — — EP claimed
EP-0446132-B1 Keratinous fibres dyeing process with 6 or 7-monohydroxyindols at acidic pH and compositions OREAL (FR) 1994-09-14 — — EP claimed
US-5203875-A Hair dyes also using ortho- and para-phenylenediamines or aminophenols; colorfastness; washfastness; perspiration resistance L'OREAL (FR) 1993-04-20 — — US claimed
WO-2022191865-A1 HAIR COLORANT ASSESSMENT, SELECTION AND FORMULATION SYSTEM Innovative Beauty LLC (US) 2022-09-15 — — WO disclosed
US-20220283032-A1 Hair Colorant Assessment, Selection And Formulation System Innovative Beauty LLC (US) 2022-09-08 — — US disclosed
US-11378457-B1 Hair colorant assessment, selection and formulation system Innovative Beauty LLC (US) 2022-07-05 — — US disclosed
US-11137291-B1 Hair colorant assessment, selection and formulation system Innovative Beauty LLC (US) 2021-10-05 — — US disclosed
US-20040158941-A1 Hair colouring and conditioning compositions THE PROCTER & GAMBLE COMPANY (US) 2004-08-19 — — US disclosed
US-20040158938-A1 Method for colouring hair THE PROCTER & GAMBLE COMPANY 2004-08-19 — — US disclosed
US-6758866-B2 AQUEOUS SOLUTION OF CHELATE COMPOUND, OXIDATION COLOR DYE AND COUPLER UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2004-07-06 — — US disclosed
US-6695888-B2 COMPLEX TRANSITION METAL HAIR DYE UNILEVER HOME & PERSONAL CARE, USA, DIVISION OF CONOPCO, INC. 2004-02-24 — — US disclosed
US-20030113286-A1 Hair colouring and conditioning compositions THE PROCTER & GAMBLE COMPANY (US) 2003-06-19 — — US disclosed
US-20030066140-A1 Transition metal complexes as dye forming catalysts in hair coloring compositions UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2003-04-10 — — US disclosed
US-6540791-B1 Oxidizer, a buffer of borates and/or alkalizing agents, a stabilizer, and a hair care ingredient such as surfactant, catalyst (enzyme), thickener, or conditioner; shelf life, bleaching performance THE PROCTER & GAMBLE COMPANY 2003-04-01 — — US disclosed
EP-1221932-A1 HAIR COLORING COMPOSITIONS AND METHODS THE PROCTER & GAMBLE COMPANY (US) 2002-07-17 — — EP disclosed
WO-2001028508-A1 HAIR COLORING COMPOSITIONS AND METHODS THE PROCTER & GAMBLE COMPANY (US) 2001-04-26 — — WO disclosed
US-5207798-A Hair dyes L'OREAL (FR) 1993-05-04 — — US disclosed
US-5203875-A Hair dyes also using ortho- and para-phenylenediamines or aminophenols; colorfastness; washfastness; perspiration resistance L'OREAL (FR) 1993-04-20 — — US disclosed
US-4566875-A HAIR DYES L'OREAL (FR) 1986-01-28 — — US disclosed
US-4289495-A HAIR DYES, STORAGE STABILITY L'OREAL (FR) 1981-09-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040158941-A1 Hair colouring and conditioning compositions FNIP1, CUTA, SHH ALDH1A1 1162/4885MAPK1 2793/4885GFER 2795/4885
US-20040158938-A1 Method for colouring hair COX5B, SHH, DNMT3A ALDH1A1 209/4885MAPK1 4327/4885GFER 2933/4885
US-20030113286-A1 Hair colouring and conditioning compositions FNIP1, CUTA, SHH ALDH1A1 1162/4885MAPK1 2793/4885GFER 2795/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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