Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CDC25B | P30305 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27946264 | 0.98 | ALDH1A1 (0.49) | KDM4EGAACA12CA14CA3 | |
| Hydrochloric Acid SCHEMBL3159285 | 0.98 | ALDH1A1 (0.49) | KDM4EGAACA12CA14CA3 | |
| SCHEMBL1755233 | 0.78 | KEAP1 (0.46) | KDM4EGAACA12CA14CA3 | |
| SCHEMBL4652710 | 0.77 | TSHR (0.48) | KDM4EGAACA12CA14CA3 | |
| SCHEMBL20715566 | 0.77 | ALDH1A1 (0.44) | KDM4EGAACA12CA14CA3 | |
| SCHEMBL3072881 | 0.77 | KDM4E (0.59) | KDM4EGAACA12CA14CA4 | |
| SCHEMBL3070481 | 0.77 | ALDH1A1 (0.53) | KDM4EGAACA12CA14CA3 | |
| SCHEMBL3072884 | 0.77 | KDM4E (0.59) | KDM4EGAACA12CA14CA4 | |
| SCHEMBL3070479 | 0.77 | ALDH1A1 (0.53) | KDM4EGAACA12CA14CA3 | |
| SCHEMBL4632499 | 0.76 | ALDH1A1 (0.47) | KDM4EGAACA12CA14CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106497797-B | Extract of fungus culture and preparation method and application thereof | 深圳大学 | 2020-02-07 | — | — | CN | disclosed |
| US-6723710-B2 | BORON GROUP-SUBSTITUTED ACYCLIC ALPHA AMINO ACIDS ARE USEFUL FOR INHIBITING A VARIETY OF ARINASE- AND NO SYNTHASE-RELATED DISORDERS, INCLUDING HEART DISEASE, GASTROINTESTINAL MOTILITY DISORDERS, AND PENILE ERECTILE DYSFUNCTION IN HUMANS. | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2004-04-20 | — | — | US | disclosed |
| US-20040063666-A1 | Compositions for inhibiting arginase activity | NATIONAL INSTITUTES OF HEALTH-DIRECTOR DEITR | 2004-04-01 | — | — | US | disclosed |
| CN-1458514-A | Nitrite detection test paper and its preparing method | HYGIENICS & ENVIRONMENT MEDICI (CN) | 2003-11-26 | — | — | CN | disclosed |
| US-20030036529-A1 | Compositions and methods for inhibiting arginase activity | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2003-02-20 | — | — | US | disclosed |
| US-6387890-B1 | CARDIOVASCULAR DISORDERS; GASTROINTESTINAL DISORDERS; SEXUAL DISORDERS | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2002-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063666-A1 | Compositions for inhibiting arginase activity | ARG1, PDE3A, ARG2 | KDM4E 713/4885GAA 165/4885CA12 2970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.