Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6697575 | 1.00 | KCNH3 (0.33) | KCNH3NAAAELANESIGMAR1EPHX1 | |
| Hydrochloric Acid SCHEMBL5854255 | 0.81 | EPHX2 (0.40) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5853189 | 0.81 | EPHX2 (0.40) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5852857 | 0.80 | EPHX2 (0.38) | ALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL5856408 | 0.78 | ADORA1 (0.36) | ALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL5853951 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL5853022 | 0.75 | ALOX5 (0.35) | ALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL5853092 | 0.74 | MAPK1 (0.42) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5852962 | 0.71 | PAX3 (0.33) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5854352 | 0.70 | ADORA1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004106394-A1 | COPOLYMERS OF ETHYLENE AND/OR α-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-12-09 | — | — | WO | disclosed |