Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26110865 | 0.98 | ALDH1A1 (0.47) | ALDH1A1POLBHPGDHSD11B1SMN1; SMN2 | |
| SCHEMBL28195034 | 0.95 | ALDH1A1 (0.43) | ALDH1A1POLBHPGDHSD11B1SMN1; SMN2 | |
| SCHEMBL4749718 | 0.85 | ALDH1A1 (0.47) | ALDH1A1POLBSMN1; SMN2TSHRMAPT | |
| SCHEMBL30443406 | 0.83 | ALDH1A1 (0.54) | ALDH1A1POLBHPGDHSD11B1SMN1; SMN2 | |
| SCHEMBL12827299 | 0.78 | ALDH1A1 (0.42) | ALDH1A1POLBHPGDHSD11B1SMN1; SMN2 | |
| SCHEMBL6697255 | 0.78 | ALDH1A1 (0.50) | ALDH1A1POLBHPGDHSD11B1SMN1; SMN2 | |
| SCHEMBL6932584 | 0.77 | TDP1 (0.56) | ALDH1A1POLBHSD11B1TSHRMAPT | |
| SCHEMBL13385998 | 0.77 | TDP1 (0.44) | ALDH1A1POLBHPGDHSD11B1SMN1; SMN2 | |
| SCHEMBL28771185 | 0.76 | ALDH1A1 (0.44) | ALDH1A1POLBHPGDHSD11B1SMN1; SMN2 | |
| SCHEMBL7575410 | 0.76 | CHRNB2 (0.47) | ALDH1A1HPGDHSD11B1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2688563-B1 | GALLIUM COMPLEXES, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE | ODONATE THERAPEUTICS LLC (US) | 2017-03-15 | — | — | EP | disclosed |
| US-20150175631-A1 | Gallium Complexes, Pharmaceutical Compositions and Methods of Use | ODONATE THERAPEUTICS, LLC | 2015-06-25 | — | — | US | disclosed |
| EP-2688563-A1 | GALLIUM COMPLEXES, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE | Genta Incorporated (US) | 2014-01-29 | — | — | EP | disclosed |
| WO-2012129473-A1 | GALLIUM COMPLEXES, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE | GENTA INCORPORATED (US) | 2012-09-27 | — | — | WO | disclosed |
| US-20120245135-A1 | Gallium Complexes, Pharmaceutical Compositions And Methods Of Use | GENTA INCORPORATED (US) | 2012-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120245135-A1 | Gallium Complexes, Pharmaceutical Compositions And Methods Of Use | COG5, CYP3A5, GPR35 | ALDH1A1 4291/4885POLB 1852/4885HPGD 1589/4885 |
| US-20150175631-A1 | Gallium Complexes, Pharmaceutical Compositions and Methods of Use | COG5, CYP3A5, GPR35 | ALDH1A1 4291/4885POLB 1852/4885HPGD 1589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.