Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.30 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.30 |
| ▸ | FNTA | P49354 | 1/20 | 0.30 |
| ▸ | FNTB | P49356 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8544631 | 0.93 | MAPK14 (0.37) | MAPK14HIF1ALTA4HMAOBRXFP1 | |
| SCHEMBL7467428 | 0.91 | MAOB (0.43) | HIF1APPARGPPARAMAOB | |
| SCHEMBL7464106 | 0.90 | HIF1A (0.35) | MEN1KMT2AHIF1A | |
| SCHEMBL7470381 | 0.87 | HTR2A (0.34) | KMT2AHIF1AFNTAFNTB | |
| SCHEMBL7494028 | 0.87 | MAPK14 (0.39) | MAPK14HIF1ALTA4HRXFP1 | |
| SCHEMBL7467539 | 0.85 | MAOB (0.46) | KMT2AHIF1AMAOB | |
| SCHEMBL7470568 | 0.83 | MAPK14 (0.38) | MAPK14MEN1KMT2AHIF1ABACE1 | |
| SCHEMBL8540309 | 0.82 | ALDH1A1 (0.36) | MAPK14MEN1KMT2AEPHX2LMNA | |
| SCHEMBL7492706 | 0.82 | HIF1A (0.42) | MAPK14MEN1KMT2AHIF1ABACE1 | |
| SCHEMBL6697613 | 0.82 | MEN1 (0.38) | MAPK14MEN1KMT2ABACE1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865424-B1 | PESTICIDES | BAYER AG (DE) | 2002-09-18 | — | — | EP | disclosed |
| EP-0865424-A1 | PESTICIDES | Novartis AG (CH) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020809-A1 | PESTICIDES | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |