Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | RAF1 | P04049 | 1/20 | 0.34 |
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | PLK4 | O00444 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7494028 | 0.94 | MAPK14 (0.39) | MAPK14HIF1ABTKTLR8TLR7 | |
| SCHEMBL7466206 | 0.93 | MAPK14 (0.36) | MAPK14HIF1ARXFP1LTA4HMAOB | |
| SCHEMBL7470381 | 0.87 | HTR2A (0.34) | HIF1ARAF1 | |
| SCHEMBL7498151 | 0.86 | HIF1A (0.46) | MAPK14HIF1ABTKTLR8TLR7 | |
| SCHEMBL7464106 | 0.86 | HIF1A (0.35) | HIF1AMAPT | |
| SCHEMBL7467428 | 0.85 | MAOB (0.43) | HIF1AMAPTMAOB | |
| SCHEMBL7467262 | 0.84 | MAPK14 (0.39) | MAPK14HIF1ABTKTLR8TLR7 | |
| SCHEMBL8544633 | 0.83 | HIF1A (0.44) | MAPK14HIF1ABTKTLR8TLR7 | |
| SCHEMBL8196231 | 0.83 | MAPK14 (0.36) | MAPK14HIF1ABTKTLR8TLR7 | |
| SCHEMBL7467539 | 0.82 | MAOB (0.46) | HIF1AMAOBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865424-A1 | PESTICIDES | Novartis AG (CH) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020809-A1 | PESTICIDES | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |