Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL23498170 | 0.84 | HRH1 (0.39) | ADRB2KEAP1LOXL2ALDH1A1KDM4E | |
| SCHEMBL14886179 | 0.69 | PLA2G10 (0.36) | ALDH1A1TSHRCYP19A1PDPK1 | |
| SCHEMBL16011605 | 0.67 | BCAT2 (0.59) | ALDH1A1KDM4E | |
| SCHEMBL6409480 | 0.65 | DPP4 (0.54) | ADRB2LOXL2ALDH1A1KDM4ENOS1 | |
| SCHEMBL29473237 | 0.65 | DPP4 (0.54) | ADRB2LOXL2ALDH1A1KDM4ENOS1 | |
| SCHEMBL3718637 | 0.65 | PTGS1 (0.49) | KEAP1LOXL2 | |
| SCHEMBL14883258 | 0.65 | BRD4 (0.32) | CYP19A1PDPK1 | |
| Ethylenediamine SCHEMBL9746025 | 0.64 | ADRB2 (0.46) | ADRB2LOXL2ALDH1A1KDM4ENOS1 | |
| Benzyl Alcohol SCHEMBL8582860 | 0.63 | TSHR (0.45) | KEAP1LOXL2ALDH1A1TSHRDPP4 | |
| SCHEMBL17681955 | 0.63 | ADORA2A (0.39) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040014687-A1 | Macrolide antibacterial compounds | ABBOTT LABORATORIES | 2004-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040014687-A1 | Macrolide antibacterial compounds | MRPL21, NOP2, PIGS | ADRB2 4380/4885KEAP1 3140/4885LOXL2 3557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.