Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | ADAMTS4 | O75173 | 4/20 | 0.44 |
| ▸ | ACLY | P53396 | 3/20 | 0.43 |
| ▸ | MMP2 | P08253 | 6/20 | 0.43 |
| ▸ | MMP9 | P14780 | 4/20 | 0.43 |
| ▸ | MMP3 | P08254 | 2/20 | 0.43 |
| ▸ | MMP13 | P45452 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 2/20 | 0.43 |
| ▸ | MMP7 | P09237 | 1/20 | 0.43 |
| ▸ | USP36 | Q9P275 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | UQCRB | P14927 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6617404 | 0.90 | MEN1 (0.44) | MEN1KMT2AGAAMAPTMAPK1 | |
| SCHEMBL6612745 | 0.87 | KCNA5 (0.46) | MEN1KMT2AGAAMAPTMAPK1 | |
| SCHEMBL7081901 | 0.86 | KMT2A (0.44) | MEN1KMT2AGAAMAPTMAPK1 | |
| SCHEMBL6613051 | 0.83 | FFAR4 (0.44) | MEN1KMT2AMAPTHTT | |
| SCHEMBL6617568 | 0.80 | GAA (0.45) | MEN1KMT2AGAAMAPTMAPK1 | |
| SCHEMBL3617302 | 0.78 | ALDH1A1 (0.61) | MEN1KMT2A | |
| SCHEMBL5831261 | 0.77 | ATM (0.55) | MEN1KMT2AGAAMAPTMAPK1 | |
| SCHEMBL5831313 | 0.77 | USP36 (0.48) | MEN1KMT2AADAMTS4MMP2MMP9 | |
| SCHEMBL6616093 | 0.76 | GAA (0.48) | MEN1KMT2AGAAMAPTMAPK1 | |
| SCHEMBL3254141 | 0.76 | ALOX12 (0.44) | MEN1KMT2AGAAADAMTS4MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030130279-A1 | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 | BIOVITRUM AB (SE) | 2003-07-10 | — | — | US | claimed |
| WO-2004112779-A1 | NEW USE VII | BIOVITRUM AB (SE) | 2004-12-29 | — | — | WO | disclosed |
| US-20030130279-A1 | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 | BIOVITRUM AB (SE) | 2003-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130279-A1 | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 | HSD11B1, HSD17B1, HSD3B1 | MEN1 770/4885KMT2A 3247/4885GAA 351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.