Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.32 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL706042 | 0.85 | ADRA2A (0.43) | ADRA2AADRA2BADRA2CCYSLTR2CYSLTR1 | |
| SCHEMBL3482119 | 0.83 | CYSLTR2 (0.47) | ADRA2AADRA2BADRA2CCYSLTR2CYSLTR1 | |
| SCHEMBL708783 | 0.81 | ADRA2A (0.51) | ADRA2AADRA2BADRA2CCYSLTR2CYSLTR1 | |
| SCHEMBL13509766 | 0.80 | TAAR1 (0.41) | TAAR1MAOACYSLTR2CYSLTR1HTR2A | |
| SCHEMBL705287 | 0.77 | MAPT (0.39) | ADRA2AADRA2BADRA2COPRM1OPRK1 | |
| SCHEMBL6699017 | 0.76 | SLC6A2 (0.42) | ADRA2ATAAR1MAOAHTR2A | |
| SCHEMBL16541142 | 0.71 | ADRA2C (0.53) | ADRA2AADRA2BADRA2C | |
| SCHEMBL705823 | 0.71 | ALOX5 (0.36) | ADRA2AADRA2BADRA2CCYSLTR2CYSLTR1 | |
| SCHEMBL3678681 | 0.71 | TAAR1 (0.50) | TAAR1MAOAHTR2AHRH1 | |
| SCHEMBL29943451 | 0.71 | TAAR1 (0.50) | TAAR1MAOAHTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274699-B1 | A PROCESS FOR PREPARING ACRYLATE-FUNCTIONAL ORGANOPOLYSILOXANE-URETHANE COPOLYMERS | WACKER-CHEMIE GMBH (DE) | 1992-07-22 | — | — | EP | disclosed |
| US-4762887-A | Process for preparing acrylate-functional organopolysiloxane-urethane copolymers | WACKER SILICONES CORPORATION (US) | 1988-08-09 | — | — | US | disclosed |
| US-4606933-A | Acrylate-functional organopolysiloxanes | SWS SILICONES CORPORATION (US) | 1986-08-19 | — | — | US | disclosed |