Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6699798 | 0.75 | ALDH1A1 (0.51) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL8687313 | 0.67 | L3MBTL1 (0.65) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4543516 | 0.65 | KDM4E (0.67) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL28135680 | 0.64 | KDM4E (0.60) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL12858639 | 0.63 | CRHBP (0.66) | ALDH1A1HPGDSMN1; SMN2MAPTPOLB | |
| SCHEMBL5426590 | 0.63 | L3MBTL1 (1.00) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9514737 | 0.62 | L3MBTL1 (0.76) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6704936 | 0.62 | MAPT (0.44) | L3MBTL1KDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL19676481 | 0.62 | KDM4E (0.54) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10085396 | 0.60 | KDM4E (0.77) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |