Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2014944 | 0.77 | ALDH1A1 (0.43) | PPARGPPARAPPARDCXCL8CNR1 | |
| SCHEMBL1046455 | 0.75 | ALDH1A1 (0.60) | PPARGPPARAPPARDCXCL8CNR1 | |
| SCHEMBL29195871 | 0.73 | ALDH1A1 (0.58) | PPARGPPARAPPARDCXCL8CNR1 | |
| SCHEMBL23519085 | 0.68 | CXCL8 (0.44) | PPARGPPARAPPARDCXCL8ALDH1A1 | |
| SCHEMBL12301773 | 0.68 | HSD11B1 (0.44) | CXCL8CNR1ALDH1A1KMT2AHPGD | |
| SCHEMBL9589205 | 0.68 | HSD11B1 (0.47) | CXCL8CNR1ALDH1A1KMT2AHPGD | |
| SCHEMBL2737124 | 0.68 | LMNA (0.43) | ALDH1A1KMT2AHPGDLMNAHTT | |
| SCHEMBL21748887 | 0.68 | SSTR4 (0.55) | PPARGPPARAPPARDKMT2AHPGD | |
| SCHEMBL4247858 | 0.67 | HSD11B1 (0.44) | CXCL8CNR1ALDH1A1KMT2AHPGD | |
| SCHEMBL11032100 | 0.67 | HPGD (0.48) | PPARGPPARAPPARDCXCL8KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2606056-A2 | HIGH-VALENT PALLADIUM FLUORIDE COMPLEXES AND USES THEREOF | President and Fellows of Harvard College (US) | 2013-06-26 | — | — | EP | disclosed |
| WO-2012024604-A2 | HIGH-VALENT PALLADIUM FLUORIDE COMPLEXES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-02-23 | — | — | WO | disclosed |