Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 11/20 | 0.40 |
| ▸ | CA9 | Q16790 | 11/20 | 0.40 |
| ▸ | CA2 | P00918 | 9/20 | 0.40 |
| ▸ | CA7 | P43166 | 5/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6699520 | 0.80 | CA12 (0.44) | CA12CA9CA2CA7CA1 | |
| SCHEMBL10921837 | 0.71 | TSHR (0.41) | KDM4ELMNA | |
| SCHEMBL6700624 | 0.68 | RET (0.30) | RETGRK5TYRO3DYRK1B | |
| SCHEMBL230481 | 0.65 | CA9 (0.50) | CA12CA9CA2CA7CA1 | |
| SCHEMBL2804664 | 0.65 | RET (0.44) | CA12CA9CA2CA7CA1 | |
| SCHEMBL27715076 | 0.63 | CHEK1 (0.56) | CA12CA9CA2CA7CA1 | |
| SCHEMBL7100055 | 0.63 | CA12 (0.41) | CA12CA9CA2CA7CA1 | |
| Saccharin SCHEMBL3661332 | 0.63 | CA12 (0.81) | CA12CA9CA2CA7CA1 | |
| Saccharin SCHEMBL10380910 | 0.63 | CA12 (0.81) | CA12CA9CA2CA7CA1 | |
| Saccharin SCHEMBL299663 | 0.63 | CA12 (0.81) | CA12CA9CA2CA7CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040137082-A1 | Compounds and methods for reducing myostatin concentration | PHOENIX LABORATORIES INC | 2004-07-15 | — | — | US | claimed |
| US-20040137082-A1 | Compounds and methods for reducing myostatin concentration | PHOENIX LABORATORIES INC | 2004-07-15 | — | — | US | disclosed |
| US-20040137083-A1 | Method for making compounds for reducing myostatin concentration | BIOTEST LABORATORIES | 2004-07-15 | — | — | US | disclosed |