Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CPT2 | P23786 | 2/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27845222 | 0.79 | HMGCR (0.46) | HMGCRCHRM1TBXA2RADRA1AALDH1A1 | |
| SCHEMBL3501612 | 0.78 | HMGCR (0.50) | HMGCRCHRM1TBXA2RADRA1AALDH1A1 | |
| SCHEMBL10940349 | 0.78 | HMGCR (0.50) | HMGCRCHRM1TBXA2RADRA1AALDH1A1 | |
| SCHEMBL22965333 | 0.76 | HMGCR (0.55) | HMGCRCHRM1TBXA2RADRA1AALDH1A1 | |
| SCHEMBL1603820 | 0.74 | HMGCR (0.46) | HMGCRCHRM1TBXA2RADRA1AALDH1A1 | |
| SCHEMBL59972 | 0.74 | ACLY (0.58) | HMGCRCHRM1TBXA2RADRA1AALDH1A1 | |
| SCHEMBL1409965 | 0.74 | ACLY (0.58) | HMGCRCHRM1TBXA2RADRA1AALDH1A1 | |
| SCHEMBL1462468 | 0.74 | ACLY (0.58) | HMGCRCHRM1TBXA2RADRA1AALDH1A1 | |
| SCHEMBL1572172 | 0.72 | HMGCR (0.50) | HMGCRCHRM1TBXA2RADRA1AALDH1A1 | |
| SCHEMBL1604921 | 0.72 | HMGCR (0.50) | HMGCRCHRM1TBXA2RADRA1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040171608-A1 | Synthesis of clasto-lactacystin beta-lactone and analogs thereof | MILLENNIUM PHARMACEUTICALS, INC. | 2004-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171608-A1 | Synthesis of clasto-lactacystin beta-lactone and analogs thereof | PSMB7, PSMB5, PSMB1 | HMGCR 2970/4885CHRM1 4423/4885TBXA2R 4627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.