SCHEMBL59972

SCHEMBL59972

CC(C)C(O)(CC(=O)O)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ACLY P53396 3/20 0.58
CPT2 P23786 2/20 0.58
HSPD1 P10809 1/20 0.47
BLM P54132 1/20 0.47
HSPE1 P61604 1/20 0.47
ALDH1A1 P00352 2/20 0.46
HMGCR P04035 1/20 0.46
CHRM1 P11229 1/20 0.46
TBXA2R P21731 1/20 0.46
ADRA1A P35348 1/20 0.46
CYP2C19 P33261 2/20 0.44
HIF1A Q16665 2/20 0.44
TSHR P16473 2/20 0.44
CYP2D6 P10635 1/20 0.44
KDM4E B2RXH2 1/20 0.34
FFAR1 O14842 1/20 0.34
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1409965 1.00 ACLY (0.58) ACLYCPT2HSPD1BLMHSPE1
SCHEMBL1462468 1.00 ACLY (0.58) ACLYCPT2HSPD1BLMHSPE1
Cadaverine Tartrate SCHEMBL9398238 0.89 ACLY (0.59) ACLYCPT2HSPD1BLMHSPE1
Malic Acid SCHEMBL29107079 0.84 SMN1; SMN2 (0.54) ACLYCPT2HSPD1BLMHSPE1
SCHEMBL13176929 0.83 CPT2 (0.40) ACLYCPT2HSPD1BLMHSPE1
SCHEMBL18283302 0.83 ACLY (0.61) ACLYCPT2HSPD1BLMHSPE1
Leucine SCHEMBL935696 0.82 SLC7A5 (0.60) ACLYCPT2HSPD1BLMHSPE1
SCHEMBL17632510 0.82 ACLY (0.50) ACLYCPT2HSPD1BLMHSPE1
Leucine SCHEMBL935695 0.82 SLC7A5 (0.60) ACLYCPT2HSPD1BLMHSPE1
SCHEMBL18283331 0.81 CPT2 (0.39) ACLYCPT2HSPD1BLMHSPE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1601 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122005693-A Application of Jiaweidanzhi Xiaoyao powder or extract thereof in preparation of medicines for treating depression complicated with ulcerative colitis 河南中医药大学 2026-05-12 CN claimed
US-12606850-B2 Synthesis of beta-hydroxyisovalerate and methods of use Sasya, Inc. (US) 2026-04-21 US claimed
US-20260096574-A1 CHOCOLATE REPLICAS PRODUCED FROM INDIVIDUAL COMPONENTS VOYAGE FOODS INC (US) 2026-04-09 US claimed
EP-4155395-B1 POLYPEPTIDE AND METHOD FOR PRODUCING L-LEUCINE USING SAME CJ CHEILJEDANG CORP (KR) 2026-03-04 EP claimed
US-20260007144-A1 CHOCOLATE REPLICAS PRODUCED FROM INDIVIDUAL COMPONENTS VOYAGE FOODS INC (US) 2026-01-08 US claimed
EP-3519579-B1 PROCESSES TO PREPARE ELONGATED 2-KETOACIDS AND C-5-C10 COMPOUNDS THEREFROM VIA GENETIC MODIFICATIONS TO MICROBIAL METABOLIC PATHWAYS DOW GLOBAL TECHNOLOGIES LLC (US) 2025-11-05 EP claimed
EP-4618772-A1 ASPERGILLUS BIOMASS CONTAINING BIOACTIVE METABOLITES Biozyme Inc. (US) 2025-09-24 EP claimed
US-20250290086-A1 TISSUE-SPECIFIC PROMOTERS IN PLANTS ALTRIA CLIENT SERVICES LLC (US) 2025-09-18 US claimed
US-20250282802-A1 PHOSPHONATE PRODUCTS AND METHODS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2025-09-11 US claimed
EP-4606226-A2 CHOCOLATE REPLICAS PRODUCED FROM INDIVIDUAL COMPONENTS Voyage Foods, Inc. (US) 2025-08-27 EP claimed
US-6605142-B1 Copper, nickel, or manganese carboxylate and colorant; ink jet printing AVECIA LIMITED (GB) 2003-08-12 US claimed
US-20030143657-A1 Methods for the identification of inhibitors of 3-isopropylmalate dehydratase as antibiotics ICORIA, INC. 2003-07-31 US claimed
WO-2003050310-A2 METHODS FOR THE IDENTIFICATION OF INHIBITORS OF ASPARAGINE SYNTHASE, 5-AMINOLEVULINATE SYNTHASE, HISTIDINOL-PHOSPHATASE, 3-ISOPROPYLMALATE AND THREONINE SYNTHASE AS ANTIBIOTICS PARADIGM GENETICS, INC. (US) 2003-06-19 WO claimed
US-20030091543-A1 Therapeutic cell preparation grafts and methods of use thereof KLEIN MATTHEW B (US) 2003-05-15 US claimed
CN-1373795-A Chemical composition for ink AVECIA LTD (GB) 2002-10-09 CN claimed
WO-2001077366-A1 POSITIVE SELECTION METHOD, COMPOUNDS, HOST CELLS AND USES THEREOF CUBIST PHARMACEUTICALS, INC. (US) 2001-10-18 WO claimed
EP-0095862-B1 FERMENTATION PROCESS FOR PRODUCTION OF ALPHA-ISOPROPYLMALIC ACID PFIZER INC. (US) 1986-07-30 EP claimed
EP-0095862-A1 Fermentation process for production of alpha-isopropylmalic acid PFIZER INC. (US) 1983-12-07 EP claimed
US-4407953-A BY YARROWIA LIPOLYTICA PFIZER INC. (US) 1983-10-04 US claimed
US-4218261-A B-HYDROXY-B-CARBOXY-ISOCAPROIC ACID AJINOMOTO COMPANY, INCORPORATED (JP) 1980-08-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260007144-A1 CHOCOLATE REPLICAS PRODUCED FROM INDIVIDUAL COMPONENTS HAAO, PTGES2, PTGES ACLY 2524/4885CPT2 456/4885HSPD1 2417/4885
US-20250282802-A1 PHOSPHONATE PRODUCTS AND METHODS CHAMP1, PHOSPHO1, RIOX2 ACLY 334/4885CPT2 2819/4885HSPD1 2366/4885
US-12606850-B2 Synthesis of beta-hydroxyisovalerate and methods of use CYP51A1, CYP4Z1, CYP2U1 ACLY 598/4885CPT2 1901/4885HSPD1 1768/4885
US-20260096574-A1 CHOCOLATE REPLICAS PRODUCED FROM INDIVIDUAL COMPONENTS HAAO, HTR6, SCD ACLY 1651/4885CPT2 1282/4885HSPD1 821/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.