Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 9/20 | 0.42 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13009915 | 0.94 | PPARD (0.39) | PPARDMRGPRX4FFAR4ALOX5PSEN1 | |
| SCHEMBL13009862 | 0.88 | FEN1 (0.39) | FFAR4PSEN1FEN1 | |
| SCHEMBL13009860 | 0.87 | MAPT (0.40) | PPARDMRGPRX4FFAR4ALOX5PSEN1 | |
| SCHEMBL6701875 | 0.87 | PPARD (0.45) | PPARDMRGPRX4FFAR4FEN1PPARG | |
| SCHEMBL6700661 | 0.86 | FFAR4 (0.42) | FFAR4FEN1 | |
| SCHEMBL2996892 | 0.86 | FFAR4 (0.42) | FFAR4PSEN1 | |
| SCHEMBL13009912 | 0.86 | SMPD1 (0.43) | FFAR4 | |
| SCHEMBL13009903 | 0.85 | MTNR1B (0.42) | FFAR4 | |
| SCHEMBL2884334 | 0.84 | PTPN1 (0.36) | PPARDMRGPRX4ALOX5PSEN1PPARA | |
| SCHEMBL13009767 | 0.82 | MEN1 (0.42) | PPARDMRGPRX4ALOX5PSEN1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040176446-A1 | Substituted amino dicarboxylic acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2004-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176446-A1 | Substituted amino dicarboxylic acid derivatives | BCAT2, BCAT1, AADAT | PPARD 439/4885RORC 2714/4885MRGPRX4 3751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.