Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 2/20 | 0.35 |
| ▸ | GIPR | P48546 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2890512 | 0.90 | MTNR1B (0.38) | MAPTRAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL13009915 | 0.88 | PPARD (0.39) | PTPN1PTPN2PTPN6MRGPRX4PSEN1 | |
| SCHEMBL2884646 | 0.88 | CCR5 (0.38) | MAPTRAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL13009860 | 0.87 | MAPT (0.40) | PTPN1PTPN2PTPN6MRGPRX4PSEN1 | |
| SCHEMBL13378441 | 0.86 | RXRB (0.43) | PTPN1PTPN2PTPN6MRGPRX4PSEN1 | |
| SCHEMBL6700714 | 0.84 | PPARD (0.42) | PTPN1PTPN2PTPN6MRGPRX4PSEN1 | |
| SCHEMBL13009767 | 0.81 | MEN1 (0.42) | MRGPRX4PSEN1SLC2A1ALOX5MAPT | |
| SCHEMBL13061697 | 0.80 | NPSR1 (0.43) | ALOX5MAPTRAB9ARXRARXRB | |
| SCHEMBL14270615 | 0.80 | ACHE (0.37) | MAPTRAB9A | |
| SCHEMBL13009731 | 0.80 | MAPT (0.39) | MAPTRAB9ARXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705043-B2 | Substituted aminodicarboxylic acid derivatives having pharmaceutical properties | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-04-27 | — | — | US | disclosed |
| US-7705043-B2 | Substituted aminodicarboxylic acid derivatives having pharmaceutical properties | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-04-27 | — | — | US | disclosed |
| US-20070179139-A1 | Substituted aminodicarboxylic acid derivatives having pharmaceutical properties | BAYER AKTIENGESELLSCHAFT (DE) | 2007-08-02 | — | — | US | disclosed |
| US-20070179139-A1 | Substituted aminodicarboxylic acid derivatives having pharmaceutical properties | BAYER AKTIENGESELLSCHAFT (DE) | 2007-08-02 | — | — | US | disclosed |
| US-20070179139-A1 | Substituted aminodicarboxylic acid derivatives having pharmaceutical properties | BAYER AKTIENGESELLSCHAFT (DE) | 2007-08-02 | — | — | US | disclosed |
| US-20040082798-A1 | Novel amino dicarboxylic acid derivatives with pharmaceutical properties | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082798-A1 | Novel amino dicarboxylic acid derivatives with pharmaceutical properties | ABAT, BCAT2, GOT1 | PTPN1 4614/4885PTPN2 4720/4885PTPN6 4729/4885 |
| US-20070179139-A1 | Substituted aminodicarboxylic acid derivatives having pharmaceutical properties | ACMSD, AADAT, DDC | PTPN1 3069/4885PTPN2 3456/4885PTPN6 3150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.