Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29758194 | 0.86 | TSHR (0.61) | TSHRLMNAALDH1A1ACHEALOX15 | |
| SCHEMBL127723 | 0.86 | TSHR (0.61) | TSHRLMNAALDH1A1ACHEALOX15 | |
| Hydrochloric Acid SCHEMBL28382242 | 0.84 | TSHR (0.59) | TSHRLMNAALDH1A1ACHEALOX15 | |
| SCHEMBL29614987 | 0.82 | HSD17B10 (0.54) | TSHRALDH1A1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL28117 | 0.82 | HSD17B10 (0.54) | TSHRALDH1A1KMT2ASMN1; SMN2TDP1 | |
| Phosphoric Acid SCHEMBL28445592 | 0.80 | TSHR (0.53) | TSHRLMNAALDH1A1ACHEALOX15 | |
| SCHEMBL6981176 | 0.77 | ALDH1A1 (0.66) | TSHRLMNAALDH1A1ACHEALOX15 | |
| SCHEMBL16812678 | 0.76 | TSHR (0.57) | TSHRLMNAALDH1A1ACHEALOX15 | |
| SCHEMBL1668771 | 0.75 | TSHR (0.47) | TSHRLMNAALDH1A1ACHEALOX15 | |
| Cadaverine Tartrate SCHEMBL28355308 | 0.75 | TP53 (0.49) | TSHRLMNAALDH1A1ALOX15GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040186132-A1 | Steroid receptor modulator compounds and methods | LIGAND PHARMACEUTICALS INCORPORATED | 2004-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040186132-A1 | Steroid receptor modulator compounds and methods | NR5A1, ESRRA, NR3C2 | TSHR 206/4885LMNA 3905/4885ALDH1A1 3161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.