Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | KMO | O15229 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | DDX3X | O00571 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29758194 | 0.87 | TSHR (0.61) | TP53TSHRLMNACES2CES1 | |
| SCHEMBL127723 | 0.87 | TSHR (0.61) | TP53TSHRLMNACES2CES1 | |
| Hydrochloric Acid SCHEMBL28382242 | 0.85 | TSHR (0.59) | TP53TSHRLMNACES2CES1 | |
| SCHEMBL6981176 | 0.81 | ALDH1A1 (0.66) | TP53TSHRLMNACES2CES1 | |
| Phosphoric Acid SCHEMBL28445592 | 0.81 | TSHR (0.53) | TP53TSHRLMNACES2CES1 | |
| SCHEMBL1668771 | 0.79 | TSHR (0.47) | TP53TSHRLMNACES2CES1 | |
| SCHEMBL28355307 | 0.77 | TSHR (0.44) | TP53TSHRLMNACES2CES1 | |
| SCHEMBL6701294 | 0.75 | TSHR (0.46) | TP53TSHRLMNACES2CES1 | |
| Cadaverine Tartrate SCHEMBL28015424 | 0.74 | TDP1 (0.59) | TSHRLMNACES2CES1ALDH1A1 | |
| SCHEMBL13857813 | 0.74 | TP53 (0.50) | TP53TSHRLMNACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115632164-A | Additive for positive electrolyte, electrolyte containing additive and application of additive | 哈尔滨工业大学 | 2023-01-20 | — | — | CN | claimed |
| CN-111154273-A | Flexible high-temperature-resistant wire and cable material and processing method thereof | 何先鹏 | 2020-05-15 | — | — | CN | claimed |
| CN-110746885-A | Sound-insulation weather-resistant waterproof coating and preparation method thereof | 湖南辰砾新材料有限公司 | 2020-02-04 | — | — | CN | claimed |
| CN-115632164-A | Additive for positive electrolyte, electrolyte containing additive and application of additive | 哈尔滨工业大学 | 2023-01-20 | — | — | CN | disclosed |
| CN-111154273-A | Flexible high-temperature-resistant wire and cable material and processing method thereof | 何先鹏 | 2020-05-15 | — | — | CN | disclosed |
| CN-110746885-A | Sound-insulation weather-resistant waterproof coating and preparation method thereof | 湖南辰砾新材料有限公司 | 2020-02-04 | — | — | CN | disclosed |