SCHEMBL8927435

SCHEMBL8927435

O=C1C=CC(=O)C(OCCC[PH](c2ccccc2)(c2ccccc2)c2ccccc2)=C1

nearest known ligand 0.58

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.58
MAOB P27338 3/20 0.58
ERBB2 P04626 1/20 0.37
PTPN1 P18031 1/20 0.34
HSD17B3 P37058 1/20 0.33
TOP1 P11387 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8927430 0.79 MAOA (0.36) MAOAMAOBTOP1
SCHEMBL14773866 0.77 GAPDH (0.49) MAOAMAOBPTPN1
SCHEMBL6701737 0.74 MAOA (1.00) MAOAMAOBERBB2HSD17B3TOP1
SCHEMBL17307112 0.73 ACHE (0.53) MAOAMAOBPTPN1HSD17B3
SCHEMBL8927456 0.73 MAOA (0.54) MAOAMAOBERBB2PTPN1HSD17B3
SCHEMBL18840117 0.73 ACHE (0.53) MAOAMAOBPTPN1HSD17B3
SCHEMBL9114285 0.71 KCNA3 (0.60)
SCHEMBL7738225 0.70 ERBB2 (0.52) MAOAMAOBERBB2PTPN1
SCHEMBL10169910 0.69 TSHR (0.36)
SCHEMBL4009820 0.68 ACHE (0.50) MAOAMAOBERBB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187791-B2 Lithographic printing plate precursor and plate making method thereof FUJIFILM CORPORATION (JP) 2012-05-29 US disclosed
US-20100075252-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PLATE MAKING METHOD THEREOF FUJIFILM CORPORATION (JP) 2010-03-25 US disclosed