Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.37 |
| ▸ | CDC25A | P30304 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23930976 | 0.95 | ALDH1A1 (0.40) | TDP1ALDH1A1TBXAS1HCAR3CYP1A2 | |
| SCHEMBL1422382 | 0.83 | ALDH1A1 (0.36) | TDP1ALDH1A1HCAR3 | |
| SCHEMBL5726023 | 0.83 | CYP11B1 (0.50) | TDP1TLR8CYP1A2CYP2C19GAA | |
| SCHEMBL8799103 | 0.81 | CYP11B1 (0.49) | TDP1TBXAS1TLR8CYP1A2CYP2C19 | |
| SCHEMBL15202361 | 0.81 | GABRA1 (0.47) | ALDH1A1CYP1A2CYP2C19CYP2C9CNR2 | |
| SCHEMBL9819383 | 0.80 | ALDH1A1 (0.44) | TDP1ALDH1A1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL23930932 | 0.78 | CYP11B1 (0.51) | TDP1ALDH1A1TLR8CYP1A2CYP2C19 | |
| SCHEMBL27922993 | 0.74 | ADORA2A (0.40) | TDP1ALDH1A1CYP1A2CYP2C19GAA | |
| SCHEMBL5105361 | 0.74 | PDE4A (0.35) | CYP1A2CYP2C19CYP2C9PDE4AADORA2A | |
| SCHEMBL31203742 | 0.73 | KDM4C (0.37) | TDP1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101550106-A | Industrialized preparation method of N-alkyl substituted-imidazole-5-carboxylic-acid/ester compound | SHANGHAI APPTEC CO LTD (CN) | 2009-10-07 | — | — | CN | disclosed |
| WO-2004078714-A2 | PROCESSES FOR PREPARING IMIDAZOQUINOXALINONES, HETEROCYCLIC-SUBSTITUTED IMIDAZOPYRAZINONES, IMIDAZOUINOXALINES AND HETEROCYCLIC-SUBSTITUTED IMIDAZOPYRAZINES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-09-16 | — | — | WO | disclosed |
| US-20040180898-A1 | Processes for preparing imidazoquinoxalinones, heterocyclic-substituted imidazopyrazinones, imidazoquinoxalines and heterocyclic-substituted imidazopyrazines | BRISTOL-MYERS SQUIBB COMPANY | 2004-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040180898-A1 | Processes for preparing imidazoquinoxalinones, heterocyclic-substituted imidazopyrazinones, imidazoquinoxalines and heterocyclic-substituted imidazopyrazines | NISCH, PDXK, IPO4 | TDP1 3206/4885ALDH1A1 3284/4885TBXAS1 437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.