SCHEMBL670187

SCHEMBL670187

CC(=O)Oc1cc2c(ccc3ccccc32)c2c1C=CC2

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.40
MAPT P10636 2/20 0.40
HPGD P15428 1/20 0.40
CYP1A2 P05177 1/20 0.39
LCK P06239 1/20 0.39
FYN P06241 1/20 0.39
ADORA3 P0DMS8 1/20 0.39
ACHE P22303 1/20 0.39
SLC6A2 P23975 1/20 0.39
AHR P35869 1/20 0.39
HTT P42858 3/20 0.38
NCEH1 Q6PIU2 5/20 0.36
TSHR P16473 1/20 0.36
GAA P10253 2/20 0.36
PGR P06401 1/20 0.36
PTGS1 P23219 1/20 0.36
MAPK1 P28482 1/20 0.36
HSD17B10 Q99714 1/20 0.36
SLC22A6 Q4U2R8 1/20 0.36
KDM4E B2RXH2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15540285 0.73 HTT (0.47) ALDH1A1MAPTHPGDHTTTSHR
SCHEMBL28689978 0.70 ALDH1A1 (0.54) ALDH1A1MAPTHPGDHTTNCEH1
SCHEMBL11152562 0.70 ALDH1A1 (0.54) ALDH1A1MAPTHPGDHTTNCEH1
SCHEMBL8368595 0.69 PAX8 (0.47) ALDH1A1HPGDCYP1A2HTTTSHR
SCHEMBL1461545 0.68 GSK3B (0.41) ALDH1A1MAPTHPGDCYP1A2LCK
SCHEMBL29946533 0.68 NCEH1 (0.69) ALDH1A1MAPTHPGDCYP1A2HTT
SCHEMBL29559115 0.68 MAPT (0.57) ALDH1A1MAPTHPGDGAAMAPK1
SCHEMBL8941764 0.68 MAPT (0.57) ALDH1A1MAPTHPGDGAAMAPK1
SCHEMBL24955836 0.67 HTT (0.60) ALDH1A1MAPTHPGDADORA3HTT
SCHEMBL12199931 0.67 MAPT (0.58) ALDH1A1MAPTHPGDCYP1A2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012022880-A2 METHOD FOR SYNTHESIZING STEROIDS UNIVERSITE DE STRASBOURG (FR) 2012-02-23 WO disclosed