Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.39 |
| ▸ | FNTA | P49354 | 2/20 | 0.38 |
| ▸ | FNTB | P49356 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 7/20 | 0.38 |
| ▸ | F7 | P08709 | 7/20 | 0.38 |
| ▸ | F3 | P13726 | 7/20 | 0.38 |
| ▸ | F10 | P00742 | 3/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.36 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6701882 | 1.00 | ITGB3 (0.39) | ITGB3ITGA2BFNTAFNTBF2 | |
| SCHEMBL6705542 | 0.85 | ITGB3 (0.38) | ITGB3ITGA2BF2F7F3 | |
| SCHEMBL6705538 | 0.85 | ITGB3 (0.38) | ITGB3ITGA2BF2F7F3 | |
| SCHEMBL6702714 | 0.85 | F2 (0.41) | ITGB3ITGA2BF2F7F3 | |
| SCHEMBL6702721 | 0.85 | F2 (0.41) | ITGB3ITGA2BF2F7F3 | |
| SCHEMBL7440145 | 0.84 | ITGB3 (0.49) | ITGB3ITGA2BF2F7F3 | |
| SCHEMBL7440166 | 0.84 | ITGB3 (0.49) | ITGB3ITGA2BF2F7F3 | |
| Hydrochloric Acid SCHEMBL6703865 | 0.83 | ITGB3 (0.42) | ITGB3ITGA2BF2F7F3 | |
| Hydrochloric Acid SCHEMBL6703856 | 0.83 | ITGB3 (0.42) | ITGB3ITGA2BF2F7F3 | |
| SCHEMBL6701009 | 0.83 | ITGB3 (0.45) | ITGB3ITGA2BF2F7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040220148-A1 | 5-Membered ring heterocycles as inhibitors of leucocyte adhesion and as VLA-4 antagonists | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-11-04 | — | — | US | disclosed |
| EP-0842943-B1 | 5-Ring heterocycles as inhibitors of leukocyte adhesion and as VLA-4 antagonists | HOECHST AG (DE) | 2003-02-26 | — | — | EP | disclosed |
| EP-0842943-A2 | 5-Ring heterocycles as inhibitors of leukocyte adhesion and as VLA-4 antagonists | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-05-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040220148-A1 | 5-Membered ring heterocycles as inhibitors of leucocyte adhesion and as VLA-4 antagonists | VCAM1, LTB4R, ITGB4 | ITGB3 23/4885ITGA2B 21/4885FNTA 1683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.