SCHEMBL6702148

SCHEMBL6702148

CCN(c1ccc(N)cc1)C(C)NS(C)(=O)=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.42
L3MBTL1 Q9Y468 4/20 0.42
TDP1 Q9NUW8 3/20 0.42
CYP3A4 P08684 2/20 0.42
MAPK1 P28482 2/20 0.42
PSMD14 O00487 1/20 0.42
TSHR P16473 1/20 0.42
RECQL P46063 1/20 0.42
GFER P55789 1/20 0.42
GAA P10253 1/20 0.36
MAPT P10636 3/20 0.36
LMNA P02545 1/20 0.36
HTT P42858 1/20 0.36
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
NR3C2 P08235 1/20 0.35
ESRRG P62508 1/20 0.34
TP53 P04637 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11391053 0.98 ALDH1A1 (0.41) ALDH1A1L3MBTL1TDP1CYP3A4MAPK1
Sulfuric Acid SCHEMBL8960974 0.96 ALDH1A1 (0.39) ALDH1A1L3MBTL1TDP1CYP3A4MAPK1
SCHEMBL10518294 0.84 TP53 (0.47) ALDH1A1CYP3A4MAPK1TSHRMAPT
Hydrochloric Acid SCHEMBL10825979 0.82 ALDH1A1 (0.34) ALDH1A1L3MBTL1TDP1CYP3A4MAPK1
SCHEMBL8081030 0.82 S100B (0.53) ALDH1A1L3MBTL1TDP1CYP3A4MAPK1
SCHEMBL793227 0.81 S100B (0.49) ALDH1A1L3MBTL1TDP1CYP3A4TSHR
SCHEMBL9847596 0.81 S100B (0.49) ALDH1A1L3MBTL1TDP1CYP3A4TSHR
Water SCHEMBL9591233 0.80 S100B (0.48) ALDH1A1L3MBTL1TDP1CYP3A4TSHR
Hydrochloric Acid SCHEMBL9188528 0.80 S100B (0.48) ALDH1A1L3MBTL1TDP1CYP3A4TSHR
SCHEMBL6536675 0.79 L3MBTL1 (0.40) ALDH1A1L3MBTL1GAAMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0506549-B1 Dyeing composition for keratinous fibers containing oxidation dye precursors and hydroxybenzofurans as couplers and dyeing process making use of such a composition OREAL (FR) 1995-10-18 EP claimed
EP-0446132-B1 Keratinous fibres dyeing process with 6 or 7-monohydroxyindols at acidic pH and compositions OREAL (FR) 1994-09-14 EP claimed
US-5203875-A Hair dyes also using ortho- and para-phenylenediamines or aminophenols; colorfastness; washfastness; perspiration resistance L'OREAL (FR) 1993-04-20 US claimed
US-20040158941-A1 Hair colouring and conditioning compositions THE PROCTER & GAMBLE COMPANY (US) 2004-08-19 US disclosed
US-6758866-B2 AQUEOUS SOLUTION OF CHELATE COMPOUND, OXIDATION COLOR DYE AND COUPLER UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2004-07-06 US disclosed
US-6695888-B2 COMPLEX TRANSITION METAL HAIR DYE UNILEVER HOME & PERSONAL CARE, USA, DIVISION OF CONOPCO, INC. 2004-02-24 US disclosed
US-20040019980-A1 One step hair coloring compositions using salts UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2004-02-05 US disclosed
US-20030135935-A1 Enhanced color deposition for hair with sequestering agents UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2003-07-24 US disclosed
US-20030066140-A1 Transition metal complexes as dye forming catalysts in hair coloring compositions UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2003-04-10 US disclosed
US-RE34697-E With cyan couplers, for sharp durable color images KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1994-08-16 US disclosed
US-5207798-A Hair dyes L'OREAL (FR) 1993-05-04 US disclosed
US-4094682-A Method for processing light-sensitive silver halide photographic material KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) 1978-06-13 US disclosed
US-4070191-A PYRAZOLONE DYES KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) 1978-01-24 US disclosed
US-4057432-A PHOTOGRAPHIC COUPLERS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) 1977-11-08 US disclosed
US-4052212-A ETHER-ESTER KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) 1977-10-04 US disclosed
US-4042393-A Silver halide emulsion containing two equivalent type coupler for use in photography KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) 1977-08-16 US disclosed
US-4028106-A CYAN COUPLER KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) 1977-06-07 US disclosed
US-4026706-A Silver halide multilayer photosensitive material KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) 1977-05-31 US disclosed
US-4008086-A PYRIDONE OR PYRIDAZONE DERIVATIVES KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) 1977-02-15 US disclosed
US-3973968-A YELLOW KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) 1976-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040158941-A1 Hair colouring and conditioning compositions FNIP1, CUTA, SHH ALDH1A1 1162/4885L3MBTL1 4256/4885TDP1 1909/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.