Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | CBX7 | O95931 | 1/20 | 0.30 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.30 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.30 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL738620 | 0.83 | SMN1; SMN2 (0.42) | SMN1; SMN2L3MBTL1L3MBTL3OPRL1KDM4E | |
| SCHEMBL2227496 | 0.80 | L3MBTL3 (0.39) | L3MBTL1L3MBTL3KDM4ETDP1ALDH1A1 | |
| SCHEMBL2227575 | 0.78 | KDM4E (0.41) | L3MBTL1L3MBTL3OPRL1KDM4ETDP1 | |
| SCHEMBL14838336 | 0.78 | KDM4E (0.41) | L3MBTL1L3MBTL3OPRL1KDM4ETDP1 | |
| SCHEMBL738738 | 0.76 | SMN1; SMN2 (0.48) | SMN1; SMN2L3MBTL1L3MBTL3OPRL1KDM4E | |
| SCHEMBL14371441 | 0.75 | KDM4E (0.36) | L3MBTL1L3MBTL3KDM4ETDP1ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL4295582 | 0.74 | SMN1; SMN2 (0.50) | SMN1; SMN2L3MBTL1L3MBTL3OPRL1KDM4E | |
| SCHEMBL737575 | 0.73 | SMN1; SMN2 (0.43) | SMN1; SMN2L3MBTL1L3MBTL3OPRL1KDM4E | |
| SCHEMBL19312789 | 0.72 | HTR6 (0.41) | L3MBTL1L3MBTL3KDM4ETDP1 | |
| SCHEMBL3168997 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117903043-A | Preparation method of cis-2-pyridine-2-yl cyclohexanol | 武威广达科技有限公司 | 2024-04-19 | — | — | CN | claimed |
| CN-117903043-A | Preparation method of cis-2-pyridine-2-yl cyclohexanol | 武威广达科技有限公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-109071749-A | Moisture-curable resin combination and assembling parts | 积水化学工业株式会社 | 2018-12-21 | — | — | CN | disclosed |
| WO-2012136772-A1 | FUSED PYRROLE DERIVATES AS ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2012-10-11 | — | — | WO | disclosed |
| US-20120157448-A1 | COMPOUNDS FOR TREATING NEURODEGENERATIVE DISEASES | GENENTECH, INC. | 2012-06-21 | — | — | US | disclosed |
| WO-2012071458-A1 | HETEROCYCLIC INHIBITORS OF BETA - SECRETASE FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | ARRAY BIOPHARMA INC. (US) | 2012-05-31 | — | — | WO | disclosed |
| US-20040142924-A1 | 6-Phenylpyridyl-2-amine derivatives useful as NOS inhibitors | PFIZER INC | 2004-07-22 | — | — | US | disclosed |
| EP-0946512-B1 | 6-PHENYLPYRIDYL-2-AMINE DERIVATIVES USEFUL AS NOS INHIBITORS | PFIZER (US) | 2003-10-08 | — | — | EP | disclosed |
| US-20020103227-A1 | 6-Phenylpyridyl-2-amine derivatives useful as NOS inhibitors | LOWE JOHN A (US) | 2002-08-01 | — | — | US | disclosed |
| US-20020032191-A1 | 6-phenylpyridyl-2-amine derivatives useful as NOS inhibitors | LOWE JOHN A (US) | 2002-03-14 | — | — | US | disclosed |
| US-6235750-B1 | NITRIC OXIDE SYNTHASE INHIBITOR | PFIZER INC | 2001-05-22 | — | — | US | disclosed |
| EP-0946512-A1 | 6-PHENYLPYRIDYL-2-AMINE DERIVATIVES USEFUL AS NOS INHIBITORS | PFIZER INC. (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998024766-A1 | 6-PHENYLPYRIDYL-2-AMINE DERIVATIVES USEFUL AS NOS INHIBITORS | PFIZER INC. (US) | 1998-06-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020032191-A1 | 6-phenylpyridyl-2-amine derivatives useful as NOS inhibitors | NOS1, NOS2, NOS3 | SMN1; SMN2 424/4885L3MBTL1 3372/4885L3MBTL3 3579/4885 |
| US-20120157448-A1 | COMPOUNDS FOR TREATING NEURODEGENERATIVE DISEASES | BACE1, PSEN1, PSEN2 | SMN1; SMN2 54/4885L3MBTL1 2745/4885L3MBTL3 4025/4885 |
| US-20040142924-A1 | 6-Phenylpyridyl-2-amine derivatives useful as NOS inhibitors | NOS1, NOS2, NOS3 | SMN1; SMN2 424/4885L3MBTL1 3372/4885L3MBTL3 3579/4885 |
| US-20020103227-A1 | 6-Phenylpyridyl-2-amine derivatives useful as NOS inhibitors | NOS1, NOS2, NOS3 | SMN1; SMN2 424/4885L3MBTL1 3372/4885L3MBTL3 3579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.