Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 8/20 | 0.46 |
| ▸ | HTR4 | Q13639 | 8/20 | 0.46 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6703008 | 0.86 | ALDH1A1 (0.41) | ACHEHTR4ALDH1A1KDM4EPARP15 | |
| SCHEMBL6698989 | 0.85 | ACHE (0.46) | ACHEHTR4ALDH1A1KDM4EPARP15 | |
| SCHEMBL27598410 | 0.83 | PARP15 (0.40) | ACHEHTR4ALDH1A1KDM4EPARP15 | |
| SCHEMBL6704355 | 0.73 | ACHE (0.44) | ACHEHTR4ALDH1A1KDM4EPARP15 | |
| SCHEMBL6701768 | 0.70 | POLB (0.50) | ALDH1A1KDM4EPARP15PARP10POLB | |
| SCHEMBL6699183 | 0.70 | PARP15 (0.54) | ALDH1A1PARP15PARP10POLBMEN1 | |
| SCHEMBL1918763 | 0.66 | LCK (0.66) | ALDH1A1KDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL6705065 | 0.65 | MMP1 (0.33) | POLBMEN1KMT2AMMP1MMP2 | |
| SCHEMBL6703970 | 0.65 | ACHE (0.43) | ACHEHTR4ALDH1A1KDM4EPOLB | |
| SCHEMBL6699193 | 0.65 | ACHE (0.46) | ACHEHTR4ALDH1A1KDM4EPARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198793-A1 | Chemical process and new intermediates | SANOFI-SYNTHELABO (FR) | 2004-10-07 | — | — | US | disclosed |
| CN-1478075-A | Chemical process and new intermediates | ��ŵ�Ѻϳ�ʵ���� | 2004-02-25 | — | — | CN | disclosed |
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |