Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | PKLR | P30613 | 1/20 | 0.44 |
| ▸ | CCKBR | P32239 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3058528 | 0.87 | ALDH1A1 (0.50) | ALDH1A1LMNATSHRMAPK1HSD17B10 | |
| SCHEMBL3071207 | 0.85 | L3MBTL1 (0.51) | PKMKMT2ASMN1; SMN2L3MBTL1PKLR | |
| SCHEMBL3069441 | 0.85 | TSHR (0.60) | ALDH1A1LMNATSHRMAPK1HSD17B10 | |
| SCHEMBL3061795 | 0.84 | ALDH1A1 (0.56) | ALDH1A1KMT2ASMN1; SMN2L3MBTL1POLB | |
| SCHEMBL6690056 | 0.80 | POLB (0.51) | ALDH1A1LMNAUSP2PKMKMT2A | |
| SCHEMBL6932063 | 0.75 | LMNA (0.44) | ALDH1A1LMNAKMT2ASMN1; SMN2CYP2C9 | |
| SCHEMBL6695770 | 0.75 | ALDH1A1 (0.56) | ALDH1A1LMNAHSD17B10USP2PKM | |
| SCHEMBL6928187 | 0.72 | ALDH1A1 (0.58) | ALDH1A1HSD17B10MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6688452 | 0.72 | PARP1 (0.48) | ALDH1A1TSHRKMT2AL3MBTL1HPGD | |
| SCHEMBL3064535 | 0.72 | L3MBTL1 (0.51) | TSHRKMT2AL3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004074438-A2 | CCR8 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-09-02 | — | — | WO | claimed |