Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 3/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.52 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.52 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.52 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.52 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.52 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.52 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.52 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16499811 | 0.87 | HTR2A (0.44) | GABRA5GABRB2SLC6A1SLC6A12SLC6A11 | |
| SCHEMBL14810346 | 0.83 | HTR2A (0.42) | GABRA5GABRB2SLC6A1SLC6A12SLC6A11 | |
| SCHEMBL27501007 | 0.83 | ITGB3 (0.44) | GABRA5GABRB2SLC6A1SLC6A12SLC6A11 | |
| Hydrochloric Acid SCHEMBL14810464 | 0.81 | HTR2A (0.41) | GABRA5GABRB2SLC6A1SLC6A12SLC6A11 | |
| SCHEMBL44579 | 0.80 | GABRA5 (0.75) | GABRA5GABRB2SLC6A1SLC6A12SLC6A11 | |
| SCHEMBL31306492 | 0.79 | GBA1 (0.36) | GABRA5GABRA1ITGB3ITGA2BL3MBTL3 | |
| SCHEMBL12881610 | 0.79 | ALDH1A1 (0.46) | GABRA5GABRB2SLC6A1SLC6A12SLC6A11 | |
| Hydrochloric Acid SCHEMBL1967312 | 0.78 | GABRA5 (0.72) | GABRA5GABRB2SLC6A1SLC6A12SLC6A11 | |
| SCHEMBL24735223 | 0.78 | L3MBTL3 (0.35) | ITGB3ITGA2BL3MBTL3L3MBTL1 | |
| SCHEMBL12883653 | 0.78 | POLB (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040192729-A1 | Carboxylic acids and the esters thereof, pharmaceutical compositions thereto and processes for the preparation thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192729-A1 | Carboxylic acids and the esters thereof, pharmaceutical compositions thereto and processes for the preparation thereof | NPY1R, ADCY1, SRD5A1 | GABRA5 280/4885GABRB2 952/4885SLC6A1 216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.