Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6712198 | 0.87 | CHRNB2 (0.31) | CHRNB2CHRNA4 | |
| SCHEMBL6712252 | 0.78 | RAD52 (0.43) | CHRNB2CHRNA4IRAK1 | |
| SCHEMBL6707015 | 0.77 | CDK7 (0.32) | CHRNB2CHRNA4 | |
| SCHEMBL5390337 | 0.76 | PRKCZ (0.37) | — | |
| SCHEMBL6712307 | 0.76 | IRAK1 (0.30) | IRAK1 | |
| SCHEMBL6708791 | 0.76 | MAPT (0.40) | CHRNB2CHRNA4 | |
| SCHEMBL6712361 | 0.74 | CDK7 (0.39) | CHRNB2CHRNA4IRAK1 | |
| SCHEMBL6710580 | 0.70 | DDB1 (0.37) | CHRNB2CHRNA4IRAK1 | |
| SCHEMBL28407956 | 0.70 | PRKCI (0.34) | — | |
| SCHEMBL7865954 | 0.67 | FCGR3B (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040074013-A1 | Oxidation dyeing composition based on 1-(4-aminophenyl) pyrrolidines substituted in positions 3 and 4, and dyeing method using same | L'OREAL S.A. (FR) | 2004-04-22 | — | — | US | claimed |
| US-20040074013-A1 | Oxidation dyeing composition based on 1-(4-aminophenyl) pyrrolidines substituted in positions 3 and 4, and dyeing method using same | L'OREAL S.A. (FR) | 2004-04-22 | — | — | US | disclosed |
| EP-1341510-A1 | OXIDATION DYEING COMPOSITION BASED ON 1-(4-AMINOPHENYL) PYRROLIDINES SUBSTITUTED IN POSITIONS 3 AND 4, AND DYEING METHOD USING SAME | L'OREAL (FR) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002045671-A1 | OXIDATION DYEING COMPOSITION BASED ON 1-(4-AMINOPHENYL) PYRROLIDINES SUBSTITUTED IN POSITIONS 3 AND 4, AND DYEING METHOD USING SAME | L'OREAL (FR) | 2002-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040074013-A1 | Oxidation dyeing composition based on 1-(4-aminophenyl) pyrrolidines substituted in positions 3 and 4, and dyeing method using same | KRT18, PYCR1, COX5A | CHRNB2 2431/4885CHRNA4 1784/4885IRAK1 4319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.