Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 3/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | CCKAR | P32238 | 1/20 | 0.33 |
| ▸ | CCKBR | P32239 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6710317 | 0.91 | ROCK1 (0.45) | TRPA1ROCK1GRM4LCKKDM1A | |
| SCHEMBL6707719 | 0.89 | ROCK1 (0.41) | TRPA1ROCK1GRM4LCKKDM1A | |
| SCHEMBL6707732 | 0.89 | ROCK1 (0.41) | ROCK1GRM4LCKLMNANSD2 | |
| SCHEMBL6709017 | 0.89 | GRM4 (0.44) | ROCK1GRM4LCKPLA2G7LMNA | |
| SCHEMBL6708854 | 0.87 | KMT2A (0.42) | PLA2G7NSD2 | |
| SCHEMBL6711762 | 0.87 | MAP3K5 (0.41) | PLA2G7LMNANSD2TP53 | |
| SCHEMBL6713406 | 0.86 | NPC1 (0.41) | PLA2G7LMNACCKARCCKBR | |
| SCHEMBL6710393 | 0.86 | TRPA1 (0.41) | TRPA1ROCK1GRM4LCKKDM1A | |
| SCHEMBL6711934 | 0.84 | PRSS12 (0.39) | PLA2G7NSD2 | |
| SCHEMBL6709008 | 0.84 | MAPT (0.36) | PLA2G7LMNANSD2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | TRPA1 594/4885ROCK1 4830/4885GRM4 4668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.