Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6710209 | 0.91 | HIF1A (0.46) | MEN1KMT2AGRIK1ALDH1A1KDM4E | |
| SCHEMBL6708097 | 0.88 | HIF1A (0.43) | GRIK1ALDH1A1HIF1A | |
| SCHEMBL6710204 | 0.88 | LMNA (0.43) | MEN1KMT2AALDH1A1KDM4EHIF1A | |
| SCHEMBL6709830 | 0.87 | BRD4 (0.39) | GRIK1HIF1AAURKA | |
| SCHEMBL6707620 | 0.86 | AURKA (0.39) | MEN1KMT2AALDH1A1KDM4EHIF1A | |
| SCHEMBL6707653 | 0.86 | HPGD (0.42) | GRIK1ALDH1A1HIF1A | |
| SCHEMBL6709887 | 0.85 | GRIK1 (0.43) | MEN1KMT2AGRIK1ALDH1A1HIF1A | |
| SCHEMBL6711725 | 0.84 | HIF1A (0.45) | MEN1KMT2AGRIK1ALDH1A1HIF1A | |
| SCHEMBL6708537 | 0.84 | ALDH1A1 (0.41) | MEN1KMT2AGRIK1ALDH1A1HIF1A | |
| SCHEMBL6709940 | 0.83 | HIF1A (0.51) | GRIK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | MEN1 4100/4885KMT2A 3181/4885GRIK1 3885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.