Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 7/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | PYGL | P06737 | 1/20 | 0.35 |
| ▸ | PYGM | P11217 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6711816 | 0.90 | PLCG2 (0.44) | MAP3K5RXFP1TP53POLBLMNA | |
| SCHEMBL6709089 | 0.89 | RXFP1 (0.38) | GPR35RXFP1HIF1ANPSR1TP53 | |
| SCHEMBL6713465 | 0.89 | GPR35 (0.43) | GPR35RXFP1HIF1ANPSR1 | |
| SCHEMBL6707722 | 0.89 | NSD2 (0.50) | GPR35RXFP1HIF1ANPSR1POLB | |
| SCHEMBL6707817 | 0.88 | GPR35 (0.35) | MAP3K5GPR35RXFP1HIF1ANPSR1 | |
| SCHEMBL6707953 | 0.87 | MAP3K5 (0.45) | MAP3K5GPR35RXFP1HIF1ANPSR1 | |
| SCHEMBL6711741 | 0.87 | HIF1A (0.47) | GPR35RXFP1HIF1ANPSR1TP53 | |
| SCHEMBL6714324 | 0.87 | PARP14 (0.42) | GPR35MAPT | |
| SCHEMBL6711486 | 0.86 | NPC1 (0.42) | RXFP1HIF1ANPSR1LMNA | |
| SCHEMBL6712039 | 0.86 | MAP3K5 (0.40) | MAP3K5RXFP1TP53POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | MAP3K5 3051/4885GPR35 2928/4885RXFP1 3836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.