Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 3/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.41 |
| ▸ | SETD2 | Q9BYW2 | 3/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6707953 | 0.89 | MAP3K5 (0.45) | NSD2RXFP1HIF1ANPSR1POLB | |
| SCHEMBL6713465 | 0.89 | GPR35 (0.43) | RXFP1HIF1ANPSR1GPR35DHODH | |
| SCHEMBL6709089 | 0.89 | RXFP1 (0.38) | NSD2RXFP1HIF1ANPSR1POLB | |
| SCHEMBL6707909 | 0.89 | MAP3K5 (0.41) | NSD2RXFP1HIF1ANPSR1POLB | |
| SCHEMBL6710194 | 0.89 | NSD2 (0.50) | NSD2RXFP1MEN1NPC1POLB | |
| SCHEMBL6711741 | 0.87 | HIF1A (0.47) | NSD2RXFP1HIF1ANPSR1MEN1 | |
| SCHEMBL6710064 | 0.87 | ALDH1A1 (0.40) | NSD2RXFP1HIF1ANPSR1MEN1 | |
| SCHEMBL6710241 | 0.86 | GPR35 (0.43) | NSD2RXFP1HIF1ANPSR1POLB | |
| SCHEMBL6710138 | 0.86 | NSD2 (0.47) | NSD2RXFP1MEN1NPC1POLB | |
| SCHEMBL6711486 | 0.86 | NPC1 (0.42) | RXFP1HIF1ANPSR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
| WO-2004018461-A2 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | NSD2 3824/4885RXFP1 3836/4885HIF1A 296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.