Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 1/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | TEK | Q02763 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6711736 | 0.94 | GPR35 (0.38) | PARP14MAPTRXFP1GPR35GRIK1 | |
| SCHEMBL6707717 | 0.91 | PARP14 (0.44) | PARP14CSNK1DMAPTMEN1KMT2A | |
| SCHEMBL6707815 | 0.90 | PARP14 (0.42) | PARP14MAPTMEN1KMT2ARXFP1 | |
| SCHEMBL6710051 | 0.90 | MEN1 (0.40) | PARP14MEN1KMT2AGPR35GRIK1 | |
| SCHEMBL6708747 | 0.89 | PARP14 (0.43) | PARP14CSNK1DMAPTMEN1KMT2A | |
| SCHEMBL6711931 | 0.89 | L3MBTL1 (0.38) | MAPTMEN1KMT2ARXFP1KCNQ2 | |
| SCHEMBL6709181 | 0.89 | GRIK1 (0.44) | CSNK1DMAPTMEN1KMT2AKCNQ2 | |
| SCHEMBL6709043 | 0.88 | GRIK1 (0.37) | MEN1KMT2AGRIK1PPARGPPARD | |
| SCHEMBL6710077 | 0.88 | CASP3 (0.38) | MAPTMEN1KMT2ARXFP1GPR35 | |
| SCHEMBL6713651 | 0.88 | MEN1 (0.44) | MEN1KMT2AGRIK1NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | PARP14 2597/4885CSNK1D 4268/4885MAPT 4754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.