Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 10/20 | 0.36 |
| ▸ | BRD2 | P25440 | 2/20 | 0.35 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | XIAP | P98170 | 1/20 | 0.35 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.35 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6710099 | 0.91 | HIF1A (0.35) | RXFP1ROCK1BRD4BRD2CREBBP | |
| SCHEMBL6713399 | 0.89 | BRD4 (0.37) | ROCK2BRD4BRD2CREBBPEP300 | |
| SCHEMBL6707969 | 0.87 | FTO (0.46) | RXFP1ROCK1BRD4BRD2BRD3 | |
| SCHEMBL6710014 | 0.84 | MAPT (0.40) | RXFP1ALDH1A1LMNAGAAMAPT | |
| SCHEMBL6711840 | 0.84 | ROCK1 (0.43) | RXFP1ROCK1ROCK2GRM4LMNA | |
| SCHEMBL6713269 | 0.82 | ROCK1 (0.42) | RXFP1ROCK1ROCK2GRM4LMNA | |
| SCHEMBL6707646 | 0.81 | RXFP1 (0.45) | RXFP1ROCK1ROCK2GRM4ALDH1A1 | |
| SCHEMBL6713205 | 0.81 | GRM4 (0.52) | RXFP1ROCK1GRM4LMNA | |
| SCHEMBL6707804 | 0.80 | MAPT (0.43) | RXFP1ROCK1GRM4ALDH1A1LMNA | |
| SCHEMBL6710337 | 0.80 | ROCK1 (0.41) | RXFP1ROCK1ROCK2GRM4HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | RXFP1 3836/4885ROCK1 4830/4885ROCK2 4868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.