Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 10/20 | 0.35 |
| ▸ | BRD2 | P25440 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6708569 | 0.91 | RXFP1 (0.39) | RXFP1BRD4BRD2CREBBPLMNA | |
| SCHEMBL6713399 | 0.89 | BRD4 (0.37) | BRD4BRD2CREBBPUSP30LMNA | |
| SCHEMBL6710487 | 0.87 | FTO (0.42) | BRD4BRD2CREBBPUSP30LMNA | |
| SCHEMBL6707869 | 0.84 | HIF1A (0.41) | HIF1ANPSR1RXFP1USP30LMNA | |
| SCHEMBL6711229 | 0.84 | MAPT (0.45) | NPSR1LMNAKMT2A | |
| SCHEMBL6711596 | 0.82 | HIF1A (0.39) | HIF1ANPSR1RXFP1LMNAKMT2A | |
| SCHEMBL6709025 | 0.81 | GRM4 (0.46) | HIF1ANPSR1RXFP1LMNAKMT2A | |
| SCHEMBL6707636 | 0.80 | GPR35 (0.46) | HIF1ANPSR1RXFP1 | |
| SCHEMBL6713231 | 0.80 | GRM4 (0.39) | HIF1ANPSR1RXFP1USP30ROCK1 | |
| SCHEMBL6711759 | 0.80 | HIF1A (0.37) | HIF1ANPSR1RXFP1LMNAROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | HIF1A 296/4885NPSR1 2999/4885RXFP1 3836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.