Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 4/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 3/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | KLK1 | P06870 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6711759 | 0.91 | HIF1A (0.37) | ROCK1HSD11B1GRM4RXFP1F10 | |
| SCHEMBL6713269 | 0.90 | ROCK1 (0.42) | ROCK1GRM4RXFP1ROCK2F10 | |
| SCHEMBL6711840 | 0.89 | ROCK1 (0.43) | ROCK1GRM4RXFP1ROCK2F10 | |
| SCHEMBL6710172 | 0.89 | ROCK2 (0.35) | ROCK1HSD11B1GRM4ROCK2LCK | |
| SCHEMBL6711396 | 0.86 | HSD11B1 (0.38) | ROCK1HSD11B1GRM4RXFP1GRM5 | |
| SCHEMBL6711766 | 0.85 | ROCK1 (0.42) | ROCK1HSD11B1GRM4RXFP1GRM5 | |
| SCHEMBL6713205 | 0.84 | GRM4 (0.52) | ROCK1GRM4RXFP1LCK | |
| SCHEMBL6707646 | 0.81 | RXFP1 (0.45) | ROCK1GRM4RXFP1ROCK2KDM4E | |
| SCHEMBL6710009 | 0.81 | LCK (0.40) | ROCK1GRM4RXFP1ROCK2LCK | |
| SCHEMBL6707804 | 0.80 | MAPT (0.43) | ROCK1GRM4RXFP1F10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | ROCK1 4830/4885HSD11B1 3068/4885GRM4 4668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.