SCHEMBL6708656

SCHEMBL6708656

O=C(Cc1ccc(-c2ccccc2)cc1)Nc1cccc2cc(C(=O)Nc3ccc(Br)cc3-c3noc(=O)[nH]3)[nH]c12

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 1/20 0.37
MEN1 O00255 5/20 0.37
KMT2A Q03164 5/20 0.37
PARP14 Q460N5 1/20 0.36
EGLN1 Q9GZT9 1/20 0.36
NSD2 O96028 1/20 0.35
NR1H4 Q96RI1 2/20 0.35
PPARG P37231 1/20 0.35
PPARD Q03181 1/20 0.35
PPARA Q07869 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6710051 0.95 MEN1 (0.40) GRIK1MEN1KMT2APARP14NSD2
SCHEMBL6711425 0.92 PARP14 (0.40) GRIK1MEN1KMT2APARP14NSD2
SCHEMBL6710077 0.92 CASP3 (0.38) GRIK1MEN1KMT2A
SCHEMBL6707655 0.92 GRIK1 (0.45) GRIK1MEN1KMT2APARP14
SCHEMBL6713651 0.92 MEN1 (0.44) GRIK1MEN1KMT2AEGLN1NR1H4
SCHEMBL6713931 0.91 GRIK1 (0.41) GRIK1MEN1KMT2ANSD2NR1H4
SCHEMBL6708772 0.91 PARP14 (0.42) GRIK1MEN1KMT2APARP14NR1H4
SCHEMBL6711736 0.90 GPR35 (0.38) GRIK1PARP14NR1H4PPARGPPARD
SCHEMBL6709043 0.90 GRIK1 (0.37) GRIK1MEN1KMT2ANR1H4PPARG
SCHEMBL6708829 0.89 PARP14 (0.42) MEN1KMT2APARP14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040142981-A1 Antibacterial benzoic acid derivatives PHARMACIA & UPJOHN COMPANY 2004-07-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040142981-A1 Antibacterial benzoic acid derivatives GABRD, PHB1, GABBR1 GRIK1 3885/4885MEN1 4100/4885KMT2A 3181/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.