Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 3/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6709861 | 0.95 | GRIK1 (0.41) | PARP14GRIK1KDM4EMEN1ALDH1A1 | |
| SCHEMBL6713394 | 0.94 | PARP14 (0.42) | PARP14GRIK1KDM4EMEN1ALDH1A1 | |
| SCHEMBL6707991 | 0.92 | PTK2B (0.41) | PARP14GRIK1KDM4EMEN1ALDH1A1 | |
| SCHEMBL6710325 | 0.92 | RXFP1 (0.40) | PARP14GRIK1RXFP1MEN1POLB | |
| SCHEMBL6707625 | 0.92 | GSK3A (0.41) | PARP14GRIK1MEN1POLBKMT2A | |
| SCHEMBL6713155 | 0.91 | SERPINE1 (0.48) | GRIK1SERPINE1KDM4ENPSR1RXFP1 | |
| SCHEMBL6708656 | 0.91 | GRIK1 (0.37) | PARP14GRIK1MEN1KMT2ANR1H4 | |
| SCHEMBL6708770 | 0.91 | GRIK1 (0.41) | PARP14GRIK1MEN1ALDH1A1POLB | |
| SCHEMBL6711858 | 0.90 | PTK2B (0.39) | PARP14GRIK1SERPINE1ALDH1A1TP53 | |
| SCHEMBL6712528 | 0.90 | GRIK1 (0.39) | PARP14GRIK1TP53PLCG2NHERF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
| WO-2004018461-A2 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | PARP14 2597/4885GRIK1 3885/4885SERPINE1 2108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.