Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRB3 | P28472 | 19/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 16/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 16/20 | 0.46 |
| ▸ | GABRP | O00591 | 11/20 | 0.46 |
| ▸ | GABRD | O14764 | 11/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 11/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 11/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 11/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 11/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 11/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 11/20 | 0.46 |
| ▸ | GABRE | P78334 | 11/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 11/20 | 0.46 |
| ▸ | GABRG1 | Q8N1C3 | 11/20 | 0.46 |
| ▸ | GABRG3 | Q99928 | 11/20 | 0.46 |
| ▸ | GABRQ | Q9UN88 | 11/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4669863 | 0.79 | GABRB3 (0.51) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL239495 | 0.78 | GABRB3 (0.60) | GABRB3GABRA2GABRB2GABRPGABRD | |
| Ammonia Solution, Strong SCHEMBL8425567 | 0.77 | GABRB3 (0.59) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL6713352 | 0.76 | GABRA2 (0.41) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7805669 | 0.75 | GABRB3 (0.49) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7819101 | 0.73 | GABRA2 (0.47) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL28073555 | 0.73 | GABRB3 (0.46) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9203511 | 0.72 | GABRA2 (0.47) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL2545891 | 0.72 | GABRA2 (0.44) | GABRB3GABRA2GABRB2GABRPGABRD | |
| Sulfurous Acid SCHEMBL28641882 | 0.72 | GABRA2 (0.57) | GABRB3GABRA2GABRB2GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0942904-B1 | 3-THIOCARBAMOYLPYRAZOLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2004-06-23 | — | — | EP | disclosed |
| US-6265430-B1 | INSECTICIDES, MITICIDES, NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-07-24 | — | — | US | disclosed |
| US-20010007876-A1 | 3-THIOCARBAMOYLPYRAZOLE DERIVATIVES AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-07-12 | — | — | US | disclosed |
| EP-0942904-A1 | 3-THIOCARBAMOYLPYRAZOLE DERIVATIVES AS PESTICIDES | BAYER AG (DE) | 1999-09-22 | — | — | EP | disclosed |
| WO-1998024769-A1 | 3-THIOCARBAMOYLPYRAZOLE DERIVATIVES AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-06-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010007876-A1 | 3-THIOCARBAMOYLPYRAZOLE DERIVATIVES AS PESTICIDES | NCS1, CYP1B1, DDT | GABRB3 1088/4885GABRA2 2821/4885GABRB2 1828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.