Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 17/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 17/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 17/20 | 0.41 |
| ▸ | GABRP | O00591 | 15/20 | 0.41 |
| ▸ | GABRD | O14764 | 15/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 15/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 15/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 15/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 15/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 15/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 15/20 | 0.41 |
| ▸ | GABRE | P78334 | 15/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 15/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 15/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 15/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 15/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6709936 | 0.81 | GABRB3 (0.58) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL6708737 | 0.76 | GABRB3 (0.46) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL7069038 | 0.74 | GABRB3 (0.43) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL6709858 | 0.73 | ALDH1A1 (0.41) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL9768335 | 0.70 | ALDH1A1 (0.52) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL10581666 | 0.68 | GABRA2 (0.54) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL7665209 | 0.67 | GABRP (0.52) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL7667394 | 0.67 | GABRP (0.62) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL7645994 | 0.66 | GABRB3 (0.55) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL3825780 | 0.65 | GABRA2 (0.58) | GABRA2GABRB2GABRB3GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0942904-B1 | 3-THIOCARBAMOYLPYRAZOLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2004-06-23 | — | — | EP | disclosed |
| CN-1105709-C | 3-thiocarbamoylpyrazole derivatives as pesticides | BAYER AG (DE) | 2003-04-16 | — | — | CN | disclosed |
| US-6265430-B1 | INSECTICIDES, MITICIDES, NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-07-24 | — | — | US | disclosed |
| US-20010007876-A1 | 3-THIOCARBAMOYLPYRAZOLE DERIVATIVES AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-07-12 | — | — | US | disclosed |
| CN-1239953-A | 3-thiocarbamoylpyrazole derivatives as pesticides | BAYER AG (DE) | 1999-12-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010007876-A1 | 3-THIOCARBAMOYLPYRAZOLE DERIVATIVES AS PESTICIDES | NCS1, CYP1B1, DDT | GABRA2 2821/4885GABRB2 1828/4885GABRB3 1088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.